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NCT ID: NCT02765503 Recruiting - Clinical trials for Squamous Cell Carcinoma of the Head and Neck

Resource Sparing Curative Radiotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck: The HYPNO Trial

HYPNO
Start date: March 2014
Phase: N/A
Study type: Interventional

The aim of the study is to test whether a resource-sparing 4-week, 20-fraction course of accelerated hypofractionated radiotherapy is non-inferior to accelerated radiotherapy delivering 33 fractions over 5.5 weeks in the treatment of patients with Stage I-IV squamous cell carcinoma of the pharynx, larynx and oral cavity with the exception of paranasal sinus, nasopharyngeal and stage I-II glottic carcinomas.

NCT ID: NCT02189538 Recruiting - Burn Injury Clinical Trials

Effect of n-3 PUFA From Fish in Enteral Nutrition of Major Burn Patients

OmegaBurn
Start date: January 2013
Phase: N/A
Study type: Interventional

Studies have shown that burn patients may benefit from low fat diets, but there is still no strong data regarding the impact of fatty acid composition used for feeding. The trial test the hypothesis that the inclusion of omega-3 PUFA in a low fat diet may improve outcome. Prospective randomised controlled trial in adult patients admitted for burns > 15% body surface area (BSA), and inhalation injury requiring mechanical ventilation and enteral nutrition. On admission randomization to receive a low-fat (18% energy as fat) modular enteral diet (LF-EN) and identical with the half of fat provided by fish oil (FO-EN). Study endpoints: mechanical ventilation time, inflammation (CRP), infectious and other complications, mortality until discharge. The study is planed as 2 parts: 1) preliminary study testing the feasibility of the study, 2) the study completed with information from the preliminary phase, both phases being randomised and controlled.

NCT ID: NCT01970189 Recruiting - Thrombocytopenia Clinical Trials

The International ITP Registry

Start date: January 2011
Phase: N/A
Study type: Observational [Patient Registry]

Primary immune thrombocytopenia (ITP) is an uncommon disease characterised by a low platelet count, which may cause the patient to have a higher risk or increased duration of bleeding. Individual hospitals only encounter a small number of ITP patients each year which makes it difficult to study this disease. By creating this disease registry, we will be able to build a more complete picture of ITP, including treatment practices, through collecting information about the condition from patients across several hospitals in several countries. Research of this kind will help future patients by providing doctors with information about ITP, and about how patients have been treated.

NCT ID: NCT00368680 Recruiting - Clinical trials for Respiratory Distress Syndrome

Early CPAP in Respiratory Distress Syndrome

Start date: January 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to establish if a strategy of EBCPAP application in a subgroup of VLBWI, 800 to 1500g birthweight, decreases the need for mechanical ventilation in this group, without affecting mortality.