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NCT ID: NCT01078051 Terminated - Clinical trials for Coronary Artery Disease

Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion (DECISION-CTO)

Start date: March 22, 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of drug-eluting stent implantation compared to optimal medical treatment in patients with chronic total occlusion.

NCT ID: NCT01077154 Terminated - Breast Cancer Clinical Trials

Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE)

Start date: June 2, 2010
Phase: Phase 3
Study type: Interventional

This randomized phase 3 trial is studying the effect of denosumab to see if it can prevent disease recurrence in the bone or in any other part of the body, when it is given as adjuvant therapy for women with early-stage breast cancer, who are at high risk of disease recurrence.

NCT ID: NCT01074606 Terminated - Cataract Clinical Trials

Visual Function After Implantation of AcrySof® Toric Lens

Start date: January 2010
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate the postoperative visual function of Taiwanese patients following bilateral or unilateral AcrySof Toric Intraocular Lens (IOL) implantation.

NCT ID: NCT01072227 Terminated - Acute Otitis Media Clinical Trials

Study to Identify and Characterize the Bacteria Causing Acute Otitis Media Episodes in Young Children in Taiwan

Start date: July 2010
Phase: N/A
Study type: Observational

The purpose of the study is to identify the bacterial aetiology of Acute Otitis Media episodes in young children aged >= 3 months to < 5 years in Taiwan

NCT ID: NCT01052090 Terminated - Clinical trials for Hepatitis C Virus Infection

Safety and Efficacy Study in Hepatitis C Patients With PHN121

ENCHAMP
Start date: September 2009
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety, tolerability and efficacy of escalating dose of PHN121 when administered orally in non-responder hepatitis C genotype 1 patients

NCT ID: NCT01051011 Terminated - Clinical trials for Diabetes Mellitus Type 2

A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy

Start date: January 2010
Phase: Phase 3
Study type: Interventional

This randomized, open-label, parallel arm study will compare the safety, tolerability and effect on glycemic control of taspoglutide versus insulin glargine in insulin-naïve patients with type 2 diabetes mellitus inadequately controlled on merformin and sulfonylurea combination therapy. Patients will be randomized to receive either taspoglutide 10mg subcutaneously (sc) weekly, or taspoglutide 10mg sc weekly for 4 weeks followed by 20mg sc weekly, or insulin glargine at an initial dose of 10 international units sc daily. Metformin treatment will be continued in all patients throughout the study, whereas sulfonylurea will be discontinued before starting study treatment. Anticipated time on study treatment is 24 weeks, with an option to continue the assigned treatment for another 28 weeks. Target sample size is 500-600 patients.

NCT ID: NCT01040455 Terminated - Clinical trials for Functional Dyspepsia

Lansoprazole for Subgroups of Functional Dyspepsia

Start date: December 2009
Phase: Phase 4
Study type: Interventional

Pharmacotherapy for functional dyspepsia remains unsatisfactory. Previous randomized trials reported conflicting results on clinical effectiveness of proton pump inhibitor in patients with functional dyspepsia. This study aims to examine whether lansoprazole 15mg is more effective than placebo for functional dyspepsia in Taiwanese patients, and to investigate the association between subgroups of patients and therapeutic response.

NCT ID: NCT01034410 Terminated - Clinical trials for Acute Myeloid Leukemia

A Study of AS1411 Combined With Cytarabine in the Treatment of Patients With Primary Refractory or Relapsed Acute Myeloid Leukemia

Start date: January 2010
Phase: Phase 2
Study type: Interventional

This is an open label randomized controlled phase II study of AS1411 combined with Cytarabine in the treatment of patients with primary refractory or relapsed acute myeloid leukemia.

NCT ID: NCT01016340 Terminated - Clinical trials for Male Oligoasthenospermia

Efficacy and Safety of MCS-5 in Treating Male Oligoasthenospermia

MCS_MOS
Start date: December 2009
Phase: Phase 2
Study type: Interventional

This is a phase II randomized, double-blind, placebo-controlled study where eligible subfertile male subjects (age 20 years).

NCT ID: NCT01015443 Terminated - Clinical trials for Non-Small Cell Lung Cancer

Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population

INSPIRE
Start date: December 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the cancer vaccine Tecemotide (L-BLP25) in addition to best supportive care is effective in prolonging the lives of Asian patients with unresectable stage III non-small cell lung cancer in comparison to a placebo plus best supportive care (a so-called Placebo controlled study).