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NCT ID: NCT02770131 Completed - Clinical trials for Hypercholesterolaemia

Chart Review of Repatha® in Subjects With Hyperlipidaemia

HEYMANS
Start date: May 4, 2016
Phase:
Study type: Observational

Review of clinical characteristics of patients who are prescribed Repatha® and how their treatment is managed.

NCT ID: NCT02763852 Completed - Parkinson's Disease Clinical Trials

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Benserazide (100/25 mg)

Start date: April 2001
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the tolerability, pharmacokinetic profile of BIA 3-202 and its metabolites, and the pharmacokinetic and pharmacodynamic interaction between 4 different single doses of BIA 3-202 (50 mg, 100 mg, 200 mg and 400 mg) and a single dose of standard levodopa 100 mg/benserazide 25 mg (Madopar® 125) in adult male and female healthy volunteers.

NCT ID: NCT02763839 Completed - Parkinson's Disease Clinical Trials

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Carbidopa (100/25 mg)

Start date: April 2001
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the tolerability, pharmacokinetic profile of BIA 3-202 and its metabolites, and the pharmacokinetic and pharmacodynamic interaction between 4 different single doses of BIA 3-202 (50 mg, 100 mg, 200 mg and 400 mg) and a single dose of standard levodopa 100 mg/carbidopa 25 mg (Sinemet® 25/100) in adult male and female healthy volunteers.

NCT ID: NCT02756611 Completed - Clinical trials for Chronic Lymphocytic Leukemia

A Study to Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

VENICE I
Start date: June 22, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of venetoclax monotherapy in participants with relapsed/refractory CLL with or without the 17p deletion or TP53 mutation, including those who have received prior treatment with a B-cell receptor inhibitor.

NCT ID: NCT02752776 Completed - Plaque Psoriasis Clinical Trials

A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.

PROSE
Start date: March 17, 2016
Phase: Phase 4
Study type: Interventional

Study of effects of secukinumab 300 mg s.c. on quality of life (QoL) in psoriasis in patients with or without prior exposure to systemic therapy.

NCT ID: NCT02748824 Completed - Clinical trials for Age-Related Macular Degeneration

Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal

AMDIncidencePT
Start date: July 2016
Phase: N/A
Study type: Observational

To assess the five-year incidence of AMD in a population from the central region of Portugal, previously phenotypically characterized.

NCT ID: NCT02746835 Completed - Fall Risk Clinical Trials

Physical Condition and Self-efficacy in People With Fall Risk

Fall Risk
Start date: September 2015
Phase: N/A
Study type: Interventional

Middle-aged or older people with fall risk were assessed and invited to a multidisciplinary falls prevention program. This program consisted on an adapted exercise program. Two sessions per week were performed, during 6 weeks supervised by a physiotherapist. At the end of this program, measures of physical condition and of self-efficacy were repeated to determine its related-effect.

NCT ID: NCT02746471 Completed - Clinical trials for Arrhythmias, Cardiac

Reveal LINQ Registry

Start date: April 2014
Phase:
Study type: Observational

The Reveal LINQ Registry will generate reliable long-term "real world" data of product performance, economic valuation, site-of-service procedural information.

NCT ID: NCT02746159 Completed - Clinical trials for Arteriovenous Fistula

Lutonix® Global AV Registry Investigating Lutonix Drug Coated Balloon for Treatment of Native and Synthetic AV Fistulae

AVR
Start date: June 7, 2016
Phase:
Study type: Observational [Patient Registry]

The purpose of this Registry is to enroll patients presenting with clinical and hemodynamic abnormalities in native or synthetic (grafts) arteriovenous (AV) fistulae located in the arm. Subjects will be treated with the Lutonix DCB carrying the CE Mark per current IFU and followed clinically for a minimum of 12 months.

NCT ID: NCT02745080 Completed - Psoriatic Arthritis Clinical Trials

Efficacy of Secukinumab Compared to Adalimumab in Patients With Psoriatic Arthritis

EXCEED 1
Start date: April 3, 2017
Phase: Phase 3
Study type: Interventional

This was a randomized, double-blind, active controlled, multicenter, parallel-group study evaluating secukinumab monotherapy and adalimumab monotherapy in approximately 850 patients with active psoriatic arthritis (PsA) who are naïve to biologic therapy and are intolerant or having inadequate response to conventional disease modifying anti-rheumatic drugs (also known as non-biologic DMARDs).