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NCT ID: NCT03147898 Completed - Pertussis Clinical Trials

Observational Study Describing the Immune Profile Induced By Pertussis Vaccines

Start date: April 12, 2017
Phase:
Study type: Observational

This is an observational study designed to describe the immune profile of toddlers and preschoolers with acellular priming after receiving a booster dose of pertussis vaccine.

NCT ID: NCT03138733 Completed - Clinical trials for Staphylococcus Aureus Bacteremia

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

Start date: August 26, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to compare the efficacy and safety of ceftobiprole medocaril versus a comparator in the treatment of patients with complicated Staphylococcus aureus bacteremia (SAB).

NCT ID: NCT03130673 Completed - Hip Fractures Clinical Trials

Challenges of Hip Fracture Care in Developing Countries. Experience at a Level 3 Center in Panama

Start date: September 1, 2014
Phase:
Study type: Observational

An observational study using the information records at the Hospital Regional Rafael Hernandez, in Chiriqui, Panama, that will help to analyze the epidemiology and early treatments results of hip fracture patients treated in this institution.

NCT ID: NCT03129672 Recruiting - Bone Neoplasm Clinical Trials

Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle

Start date: May 20, 2014
Phase:
Study type: Observational

The study show the clinical results of limb salvage for primary malignant bone tumor of the distal tibia using block excision of the tumor and reconstruction with allograft arthrodesis with different methods of fixation (plates or intramedullary nail system)

NCT ID: NCT03110770 Completed - Virus Diseases Clinical Trials

VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents

DNA
Start date: March 29, 2017
Phase: Phase 2
Study type: Interventional

This was a multicenter, randomized study to evaluate the safety, immunogenicity, and efficacy of VRC-ZKADNA090-00-VP (Zika virus wildtype DNA vaccine) or placebo. In Part A, the primary objective was to evaluate the safety and tolerability of the vaccine in different vaccination regimens. In Part B, the primary objectives were to evaluate the safety and efficacy of the vaccine compared to placebo.

NCT ID: NCT03092791 Terminated - Poliomyelitis Clinical Trials

IPV-102 Safety, Tolerability and Immunogenicity of TAK-195 in Healthy Infants, Toddlers and Adults

Start date: June 7, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to select the optimal antigen dosage of the three Sabin poliovirus strains (types 1, 2, and 3) entering the composition of the stand-alone trivalent Sabin-based inactivated poliomyelitis vaccine (sIPV) to take forward into advanced stage studies. The selection will be carried out comparing the three sIPV study arms based on the safety and tolerability profile after each dose of primary immunization and the immune response to poliovirus types 1, 2, and 3 for both Sabin and Salk strains, after the final dose of a three dose primary immunization series (Day 85).

NCT ID: NCT03028194 Completed - Pre-Eclampsia Clinical Trials

Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

Use of Postpartum uterine curettage in reducing hospitalization time or in improving the clinical evolution of the patient with preeclampsia/eclampsia.

NCT ID: NCT03027297 Active, not recruiting - HIV-1 Infections Clinical Trials

TMC114IFD3001 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir(Rtv) in HIV1 Infected Adults, Adolescents and Children Aged 3 Years or Above and Coming From Previous Company Sponsored Studies With DRV

Start date: August 2011
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to continue the provision of darunavir/ low-dose ritonavir (DRV/rtv) to adult and pediatric patients who previously received DRV/rtv in the clinical trials TMC114-C211, TMC114-C214, TMC114-TiDP31-C229 or in the pediatric trial TMC114-TiDP29-C232 who continue to benefit from the use of DRV/rtv, in countries where DRV is not commercially available for the subject, is not reimbursed, or cannot be accessed through another source (e.g., access program, governmental program).

NCT ID: NCT03025750 Completed - Poliomyelitis Clinical Trials

Safety and Immunogenicity of Adjuvanted Reduced Dose Inactivated Polio Vaccine in 2, 4, 6 Months of Age

VIPV-07
Start date: January 19, 2017
Phase: Phase 3
Study type: Interventional

The trial is a phase III, non-inferiority, observer-blind, randomised, active controlled, multicentre clinical trial with 2 parallel groups: IPV-Al SSI (investigational vaccine) and IPV SSI (comparator vaccine). The vaccines will be administered at 2, 4 and 6 months of age.

NCT ID: NCT02984423 Completed - Ovarian Cancer Clinical Trials

FLABRA: Frontline Approach for BRCA Testing in OC Treatment naïve Population. A LATIN AMERICA Epidemiologic Study

FLABRA
Start date: December 27, 2016
Phase:
Study type: Observational

This study aims to answer very important questions regarding the prevalence of somatic and germline mutations (sBRCAm and gBRCAm) in a population of newly diagnosed ovarian cancer patients from Latin America. These answers may be extremely helpful in the counseling for genetic risk and treatment approach in these populations and will aid in making treatment decisions in the future