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NCT ID: NCT06232707 Withdrawn - Multiple Myeloma Clinical Trials

A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

ALUMMINATE
Start date: May 3, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of alnuctamab compared to standard of care regimens in participants with relapsed or refractory multiple myeloma (RRMM).

NCT ID: NCT05580250 Withdrawn - Healthy Clinical Trials

A Study of LY3526318 in Healthy Male Japanese Participants

Start date: November 22, 2022
Phase: Phase 1
Study type: Interventional

This is a study of LY3526318 in healthy male Japanese. The main purposes of this study are to: - Assess how safe and well tolerated LY3526318 is when given by mouth. - Measure how LY3526318 affects the kidney and the liver. The study will be conducted in three parts (Part A, Part B, Part C). Participants may only enroll in one part. After screening, the study will last from one to two weeks, depending on part.

NCT ID: NCT05159128 Withdrawn - Healthy Clinical Trials

A Study of JNJ-75105186 in Healthy Japanese and Chinese Participants

Start date: November 15, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of JNJ-75105186 after single ascending oral dose administration in healthy Japanese participants and after single oral dose administration in healthy Chinese participants.

NCT ID: NCT04892888 Withdrawn - Clinical trials for Coronavirus Disease (COVID-19)

Survey of the Moderna COVID-19 Vaccine in People at High-Risk of Developing Severe COVID-19 Symptoms

Start date: August 1, 2022
Phase:
Study type: Observational

This study is a survey of the Moderna COVID-19 vaccine in Japanese people at high risk of developing severe COVID-19 symptoms. The study sponsor will not be involved in how the participants are treated but will provide instructions on how the clinics will record what happens during the study. The main aim of the study is to check for side effects of the Moderna COVID-19 vaccine in this group. This will be from the first vaccination to 28 days after the second vaccination. The number of visits to the clinic will depend on the clinic's standard practice.

NCT ID: NCT04740970 Withdrawn - Alopecia Areata Clinical Trials

A Study of JNJ-64304500 in Participants With Alopecia Areata

Start date: March 24, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the clinical response of 22 weeks of study intervention with JNJ-64304500, compared with placebo, in participants with moderate to severe alopecia areata (AA).

NCT ID: NCT03878953 Withdrawn - Clinical trials for Chronic Hypoparathyroidism

A Clinical Study of rhPTH(1-84) Treatment in Japanese Participants With Chronic Hypoparathyroidism

Start date: August 31, 2022
Phase: Phase 3
Study type: Interventional

This clinical study aims to evaluate the safety and efficacy of repeated dosing of recombinant human parathyroid hormone (rhPTH[1-84]) in Japanese participants with chronic hypoparathyroidism for a 26-week period.

NCT ID: NCT03699176 Withdrawn - Uterine Fibroids Clinical Trials

Assessment of Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids

ASTEROID 7
Start date: October 27, 2018
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to show superiority of vilaprisan in the treatment of heavy menstrual bleeding (HMB) in subjects with uterine fibroids compared to placebo.The secondary objectives of this study are to additionally evaluate the efficacy and safety of vilaprisan in subjects with uterine fibroids.

NCT ID: NCT03592862 Withdrawn - Clinical trials for Dementia With Lewy Bodies

A Study to Assess Safety, Tolerability, and Efficacy of HTL0018318 in Patients With Dementia With Lewy Bodies

DLB
Start date: July 2019
Phase: Phase 2
Study type: Interventional

To establish the safety and efficacy of HTL0018318 compared with placebo when administered once daily for 12 weeks to patients with dementia with Lewy bodies.

NCT ID: NCT03536182 Withdrawn - Clinical trials for Locally Advanced Pancreatic Adenocarcinoma

Trial of Carbon Ion Versus Photon Radiotherapy for Locally Advanced, Unresectable Pancreatic Cancer

CIPHER
Start date: May 29, 2019
Phase: Phase 3
Study type: Interventional

To determine if carbon ion radiotherapy improves overall survival versus photon therapy in patients with locally advanced, unresectable pancreatic cancer

NCT ID: NCT03502694 Withdrawn - Metapneumovirus Clinical Trials

Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Oral Lumicitabine Regimens in Hospitalized Adult Participants Infected With Human Metapneumovirus

STEP
Start date: November 5, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine in hospitalized adult participants infected with human metapneumovirus (hMPV - a virus closely related to respiratory syncytial virus (RSV) and has been identified as an important cause of acute respiratory infections, affecting all age groups) the dose-response relationship of multiple regimens of lumicitabine on antiviral activity based on nasal hMPV shedding using quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) assay.