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NCT ID: NCT02987855 Withdrawn - Fibromyalgia Clinical Trials

Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia

ADcSVF-CRPS
Start date: December 15, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time. They appear to be dysregulation of the central nervous system (CNS) and the autonomic system (sympathetic/parasympathetic) which cause extensive functional losses, impairment, and disabilities. They are often associated with injury sites (including surgical) which produce constant, often disabling pain and motor-sensory losses. Treatments are often ineffective and include medications (often high dose opiates), Physical Therapy (PT), and surgical interventions (sympathectomy, ablation) or insertion stimulators of the CNS. Study is an interventional study to document the safety and efficacy of use of adipose-derived cellular stromal vascular fraction (AD-cSVF) in chronic pain and dysfunction disease groups.

NCT ID: NCT02939859 Withdrawn - Multiple Sclerosis Clinical Trials

Use of Cellular Stromal Vascular Fraction in Multiple Sclerosis,Autoimmune, Inflammatory, Neurologic Conditions

cSVF
Start date: December 15, 2018
Phase: Phase 1
Study type: Interventional

Purpose of study is to determine safety and efficacy of use of autologous Adipose-Derived cellular Stromal Vascular Fraction (AD-cSVF) suspended in Normal Saline and delivered via intravascular system of quality of life and alteration of documented Muscular Sclerosis (MS) and related neurodegenerative patients. It is believed that the heterogeneous cell population which includes multipotent stem/stromal cells are capable of immune modulation/inflammatory modulation properties. Exam of disease progression and quality of life changes will be evaluated.

NCT ID: NCT02796066 Withdrawn - Acne Vulgaris Clinical Trials

TSN2898-201 Safety and Efficacy of TSN2898 in the Treatment of Acne Vulgaris

Start date: June 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of TSN 2898 topical gel in the treatment of moderate to severe acne.