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NCT ID: NCT04358653 Completed - Clinical trials for Functionality, Falls, Elderly, Fall Prevention, Exercise Elderly, Assessment, Rehabilitation, Community-Dwelling

Exercise Effectiveness on Fall Risk Factors

Start date: October 3, 2018
Phase: N/A
Study type: Interventional

Objective: To assess the effectiveness of an intervention exercise program on enhancing fall risk deterrent factors, such as balance, postural control, overall strength, functionability in community-dwelling individuals. Design: Single-blinded randomized controlled trial, comparing two groups, with follow-ups at the begging and 15 days after the completion of the program Setting: Nursing homes in Ano Volos and Kanalia Participants: A total of 40 elderly people, both male and female, aged 65 years and older were randomly assigned to an intervention exercise group (n = 20) and a control group (n = 20). Interventions: Intervention exercise program consisted of two sessions each week for 8 consecutive weeks. The control group received no exercise intervention. Measurements: Main outcomes were measured by the Timed Up and Go Test, Berg Balance Scale, 10-second chair stand test, Saehan hand grip dynamometer, Upper and Lower Limp reach tests.

NCT ID: NCT04357366 Completed - COVID-19 Clinical Trials

suPAR-guided Anakinra Treatment for Validation of the Risk and Management of Respiratory Failure by COVID-19 (SAVE)

SAVE
Start date: April 15, 2020
Phase: Phase 2
Study type: Interventional

In the SAVE study patients with lower respiratory tract infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at high risk for progression to serious respiratory failure will be detected using the suPAR biomarker. They will begin early treatment with anakinra in the effort to prevent progression in serious respiratory failure.

NCT ID: NCT04356092 Completed - Ischemia Limb Clinical Trials

2D Perfusion DSA for the Quantification of Infrapopliteal Angioplasty

Start date: May 2, 2017
Phase: N/A
Study type: Interventional

A custom-made, 2D-perfusion digital subtraction angiography (PDSA) algorithm has been designed and implemented towards foot perfusion quantification following endovascular treatment of critical limb ischemia (CLI), in order to assist intra-procedural decision-making and enhance clinical outcomes.

NCT ID: NCT04350047 Completed - Clinical trials for Renal Cell Carcinoma Stage III

Renal Cell Carcinoma and Stage IV Inferior Vena Cava Thrombus: Resection Without Thoracotomy

Start date: January 1, 2018
Phase:
Study type: Observational

Assessment of short-term outcomes of radical nephrectomy combined with IVC thrombectomy with a novel technique without thoracotomy: single center case series.

NCT ID: NCT04346758 Completed - Postoperative Pain Clinical Trials

Ultrasound-assisted Shamrock Method for Lumbar Plexus Nerve Block in Elderly Trauma Patients, Revisited.

Start date: February 15, 2020
Phase: N/A
Study type: Interventional

A revised ultrasound-guided approach to the lumbar plexus is investigated as for efficacy and safety in elderly trauma patients undergoing operations of the lower extremeties.

NCT ID: NCT04346459 Completed - Tracheal Intubation Clinical Trials

Three Different Techniques for Tracheal Intubation Via Supraglottic Airway Devices

Start date: January 10, 2020
Phase: N/A
Study type: Interventional

This study compares three different supraglottic airway devices used as a conduit for tracheal intubation in order το determine which one achieves the highest success rate of first attempt intubation

NCT ID: NCT04344990 Completed - Postoperative Pain Clinical Trials

Postoperative Pain Management After Total Knee Arthroplasty

Start date: June 29, 2015
Phase: N/A
Study type: Interventional

The study compares three different analgesic techniques in order to determine which one serves as the optimal method for postoperative pain management after Total Knee Arthroplasty in patients suffering from Osteoarthritis

NCT ID: NCT04339712 Completed - COVID-19 Clinical Trials

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction

ESCAPE
Start date: April 2, 2020
Phase: Phase 2
Study type: Interventional

Our aim is to conduct one trial of personalized immunotherapy in patients with SARS-CoV-2 (COVID-19) associated with organ dysfunction and with laboratory findings of macrophage activation syndrome or immune dysregulation. These patients will be selected by the use of a panel of biomarkers and laboratory findings and they will be allocated to immunotherapy treatment according to their needs.

NCT ID: NCT04338321 Completed - Clinical trials for Depressive Disorder, Major

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder

ESCAPE-TRD
Start date: August 21, 2020
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to evaluate the efficacy of flexibly dosed esketamine nasal spray compared with quetiapine extended-release (XR), both in combination with a continuing selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor (SSRI/SNRI), in achieving remission in participants who have treatment-resistant major depressive disorder (MDD) with a current moderate to severe depressive episode.

NCT ID: NCT04330053 Completed - Exercise Clinical Trials

Documentation of Fall Incidents and Application of a Fall Prevention Programme for Seniors in Northern Greece

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Due to the aging of the earth's population in the coming years, strategies for preventing falls in the elderly are of increasing research interest. Injuries due to falls have a direct impact on the quality of life of the elderly and are associated with very high costs for the healthcare system. However, few organized fall prevention interventions have been implemented in Greece, unlike other EU countries. The systematic recording of falls, the information and education of older people about injury prevention and the participation of older people in organized fall coping strategies in Greece are almost non-existent. Group exercise programs have proven to be effective in reducing falls. The OTAGO exercise program has shown that it can effectively reduce the number of falls in the elderly by up to 54%. However, its widespread implementation by a government agency in Greece such as the Elderly Day Care Centers (EDCC) has not yet been possible.