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NCT ID: NCT06207227 Completed - Vaginal Atrophy Clinical Trials

Clinical Performance and Safety of the VITA AV Clinical System

Start date: April 13, 2023
Phase: N/A
Study type: Interventional

The primary objective of this clinical investigation is to demonstrate that treatment with the VITA AV clinical system is feasible and to evaluate clinical performance and safety when used to improve the symptoms and signs of vaginal atrophy (VA) due to menopause.

NCT ID: NCT06174623 Not yet recruiting - Heart Failure Clinical Trials

Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance

Start date: August 2024
Phase: N/A
Study type: Interventional

Evaluation of the safety and efficacy of the ModulHeart System in patients hospitalized with acute decompensated heart failure (ADHF) and diuretic resistance

NCT ID: NCT06159790 Recruiting - Metastatic NSCLC Clinical Trials

A Study to Compare Efficacy, Safety, and Immunogenicity of GME751 and EU-authorized Keytruda in Adult Participants With Untreated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)

Start date: April 29, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy, safety, and immunogenicity of GME751 compared with Keytruda® (pembrolizumab) in participants with untreated metastatic non-squamous NSCLC (irrespective of PD-L1 status), without sensitizing EGFR or ALK mutations.

NCT ID: NCT06154330 Recruiting - Clinical trials for Glaucoma, Open-Angle

Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation Glaucomas

Start date: November 20, 2023
Phase:
Study type: Observational

To assess safety and efficacy of a novel suprachoroidal silicone tube (SST) shunt for the treatment of primary open angle and exfoliative glaucomas.

NCT ID: NCT06137820 Active, not recruiting - Clinical trials for Ankle Injury or Chronic Trauma to the Ankle

CETI-ANKLE: Cetilar®️ in Patients With Ankle Injury or Chronic Trauma to the Ankle

Start date: November 18, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and efficacy of Cetilar®

NCT ID: NCT06134115 Completed - Clinical trials for Primary Knee Osteoarthritis Grade 3 - 4

LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4

Start date: August 19, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and efficacy of Lipocet® (food supplement) in patients with primary knee osteoarthritis grade 3 - 4

NCT ID: NCT06127043 Recruiting - Ulcerative Colitis Clinical Trials

A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Ulcerative Colitis (ROSETTA)

Start date: December 4, 2023
Phase: Phase 2
Study type: Interventional

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)

NCT ID: NCT06103539 Not yet recruiting - Clinical trials for Heart Failure With Reduced Ejection Fraction

Pacertool Early Feasibility Study - Safety and Performance

Start date: December 1, 2023
Phase:
Study type: Observational

The study is a non-randomized, two-part, open label, prospective single-site, single arm, safety and performance study. The study is designed to collect acute and long-term clinical data and user reported outcome data from using the PreSens-Catheter and PACER Software during cardiac catheterization and Cardiac Resynchronization Therapy (CRT) device implantation procedures. Subjects with indication for arterial catheterization and CRT will be included.

NCT ID: NCT06099548 Active, not recruiting - Clinical trials for High-Risk Percutaneous Coronary Intervention

Magenta Elevate™ First-in-Human Clinical Study in High-Risk PCI Patients

ELEVATE I
Start date: December 17, 2020
Phase: N/A
Study type: Interventional

The Elevate™ First-In-Human (FIH) study is designed to evaluate the initial safety and device functionality of the Elevate™ percutaneous Left Ventricular Assist Device (pLVAD) System in patients undergoing non-emergent, high-risk percutaneous coronary interventions.

NCT ID: NCT06099106 Recruiting - Atrial Fibrillation Clinical Trials

Safety and Performance of ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The study is designed to evaluate the safety and performance of the ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device in Patients with non-valvular Atrial Fibrillation, who are at increased risk for stroke, and that cannot take, or have a reason to seek an alternative, to long-term anticoagulation therapy. Potential patients who are candidates for LAA closure will be screened to confirm that all inclusion/exclusion criteria are met, with final eligibility confirmation on day of procedure. All enrolled subjects who went through the procedure will be followed during the procedure to hospital discharge. Additional follow up time points are scheduled at 45 days, 6 months and 12 months post procedure.