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NCT ID: NCT00831441 Terminated - Clinical trials for Acute Coronary Syndrome

Phase III Acute Coronary Syndrome

APPRAISE-2
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if apixaban is superior to placebo for preventing cardiovascular death, non-fatal myocardial infarction, or ischemic stroke in subjects with a recent acute coronary syndrome

NCT ID: NCT00827008 Terminated - Subjective Tinnitus Clinical Trials

Open-Label, Long-Term Treatment Study, to Assess the Long-Term Safety and Tolerability and Efficacy of Neramexane in Patients With Subjective Tinnitus

OLLTT
Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the long-term safety and tolerability and efficacy of neramexane mesylate in the long-term treatment of subjective tinnitus after a completed double-blind randomized placebo controlled study

NCT ID: NCT00825058 Completed - Clinical trials for Major Depressive Disorders

Efficacy and Safety of SR58611 Compared to Placebo and Paroxetine

Start date: November 2003
Phase: Phase 3
Study type: Interventional

Primary objective : - To demonstrate the antidepressant efficacy on the Hamilton Depression Rating Scale of SR58611A 700mg/day compared with placebo in the treatment of patients with a recurrent major depressive episode. Secondary objectives: - To assess the safety profile of SR58611A 700 mg/d in comparison to placebo and to assess plasma concentrations of the active metabolite.

NCT ID: NCT00824460 Completed - Clinical trials for Chronic Kidney Disease

Study of Phosphate Levels in Patients With Chronic Kidney Disease

PA21
Start date: December 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the ability of different doses of PA21 to lower serum phosphate levels, in patients with chronic kidney disease on maintenance hemodialysis.

NCT ID: NCT00824447 Completed - Clinical trials for Allergic Rhinoconjunctivitis

Long-term Efficacy and Safety Study With Oralgen Grass Pollen

Start date: August 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This study is designed to give additional information on the efficacy, safety and local effects (tolerability) of a dose of sublingual immunotherapy administered once a day, during a second grass pollen season.

NCT ID: NCT00821093 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Safety and Efficacy of Indacaterol Once Daily Versus Salmeterol Twice Daily in Chronic Obstructive Pulmonary Disease (COPD)

INSIST
Start date: January 2009
Phase: Phase 3
Study type: Interventional

This study compared the safety and efficacy of indacaterol 150 µg taken once daily (o.d.) versus salmeterol 50 µg taken twice daily (b.i.d) in patients 40 years old or older with chronic obstructive pulmonary disease.

NCT ID: NCT00820911 Completed - Clinical trials for Kidney Transplantation

Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients

Start date: September 2008
Phase: Phase 2
Study type: Interventional

This study will assess safety and efficacy of AEB071 combined with everolimus in a CNI-free (calcineurin inhibitor) regimen in renal transplant recipients.

NCT ID: NCT00819767 Completed - Hypertension Clinical Trials

Efficacy and Safety of Aliskiren in Patients With Mild to Moderate Hypertension During Exercise

Start date: February 2009
Phase: Phase 2
Study type: Interventional

This study compared the blunting effect of aliskiren and valsartan monotherapies on exercise-induced rises in systolic blood pressure in patients with mild to moderate essential hypertension.

NCT ID: NCT00814307 Completed - Clinical trials for Arthritis, Rheumatoid

A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis

Start date: February 2009
Phase: Phase 3
Study type: Interventional

This Phase 3 study is intended to provide evidence of the efficacy and safety of CP 690,550 when dosed 5 mg and 10 mg twice a day as monotherapy in adult patients with moderate to severe Rheumatoid Arthritis. It is intended to confirm the benefits of CP-690,550 in improving signs and symptoms and physical function that were observed in the Phase 2 Rheumatoid Arthritis studies.

NCT ID: NCT00813709 Completed - Multiple Sclerosis Clinical Trials

Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)

REFLEXION
Start date: December 2008
Phase: Phase 3
Study type: Interventional

REFLEXION is a double blind extension of the study 27025 (NCT00404352) (REFLEX). The purpose of the study is to obtain long-term follow-up data in subjects with clinically definite multiple sclerosis (MS) and subjects with a first demyelinating event at high risk of converting to MS, treated with fetal bovine serum [FBS]-free/human serum albumin [HSA]-free formulation of interferon [IFN]-beta-1a (RNF).