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NCT ID: NCT05687461 Active, not recruiting - Quality Control Clinical Trials

Construction of a National Diagnosis and Treatment Quality Control Platform for Major Respiratory Diseases

Start date: July 1, 2022
Phase:
Study type: Observational

1. Build a national diagnosis and treatment quality control platform for major respiratory diseases It will establish and improved a "National diagnosis and Treatment quality control Platform for major respiratory diseases", and form a three-level network of diagnosis and treatment quality control for major respiratory diseases with a three-level system structure of "national, provincial and hospital". 2. Promote standardized diagnosis and treatment techniques for major respiratory diseases Relying on the specialized disease collaboration group or innovative unit model, all-round and hierarchical precision training and teaching are carried out to popularize and promote standardized diagnosis and treatment technology schemes for major respiratory diseases, so as to achieve the homogenization of diagnosis and treatment level for major respiratory diseases.

NCT ID: NCT05687201 Active, not recruiting - Clinical trials for Intracerebral Hemorrhage

Effect of Apolipoprotein E on the Prognosis of Patients With Intracerebral Hemorrhage

Start date: January 1, 2020
Phase:
Study type: Observational

The purpose of this observational study was to compare perihematomal edema and short-term prognosis in patients with intracerebral hemorrhage carrying the APOE-ε3 and APOE-ε4 genes. The main questions it aims to answer are: - Exploring whether patients carrying the ApoE-ε4 gene have more perifocal perihematomal edema after intracerebral hemorrhage than patients with the ApoE-ε3 gene. - ApoEε4 gene has worse short-term prognosis than ApoEε3 gene in intracerebral hemorrhage patients. All the patients in this study received the same medications based on the guidelines for the management of hypertensive intracerebral hemorrhage.Some ICH patients were evaluated for Stereotactic minimally invasive surgery (sMIS) treatment by two experienced neurosurgeons.

NCT ID: NCT05687032 Active, not recruiting - Clinical trials for Acute Lymphoblastic Leukemia

A Study of Inotuzumab Ozogamicin in Chinese Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Start date: February 24, 2023
Phase: Phase 4
Study type: Interventional

This is an open-label, single-arm, multicenter study in Chinese patients with relapsed or refractory CD22-positive B-cell ALL. The objective of the study is to confirm the efficacy, safety, and PK of inotuzumab ozogamicin in patients with relapsed or refractory B-cell ALL from mainland China.

NCT ID: NCT05683353 Active, not recruiting - Clinical trials for SARS-CoV-2 Infection

Mechanism and Immune Function Analysis of SARS-CoV-2 Infection in Hematologic Tumors

Start date: December 14, 2022
Phase:
Study type: Observational

The goal of this observational study is to compare the immune function and infection mechanism of patients with hematologic tumors and those people without underlying diseases after infection with SARS-CoV-2. Clinical characteristics, treatment options and responses will be collected. Peripheral blood will be collected from patients with hematologic tumors infected with SARS-CoV-2 and those people without underlying diseases infected with SARS-CoV-2.

NCT ID: NCT05682950 Active, not recruiting - Clinical trials for Endometrial Neoplasms

Optimal Margin Evaluation of Online Adaptive Radiotherapy for Postoperative Treatment of Endometrial and Cervical Cancer

Start date: September 12, 2022
Phase: Phase 2
Study type: Interventional

Online adaptive radiotherapy has demonstrated to be feasible to reduce inter-fractional radiotherapy errors as it re-optimizes treatment plan every fraction. To investigate the extent and value of margin reduction,we conduct a prospective clinical trial to determine the optimal margin and toxicity of smaller margin.

NCT ID: NCT05682105 Active, not recruiting - Clinical trials for Artificial Intelligence

Detection of Jaundice From Ocular Images Via Deep Learning

Start date: December 1, 2018
Phase:
Study type: Observational

Our study presents a detection model predicting a diagnosis of jaundice (clinical jaundice and occult jaundice) trained on prospective cohort data from slit-lamp photos and smartphone photos, demonstrating the model's validity and assisting clinical workers in identifying patient underlying hepatobiliary diseases.

NCT ID: NCT05680155 Active, not recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Placebo in T2DM Patients

Start date: December 29, 2022
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to investigate the efficacy and safety of XW003 versus placebo in patients with type 2 diabetes mellitus (T2DM) inadequately controlled by diet and exercise alone

NCT ID: NCT05680129 Active, not recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM

Start date: January 10, 2023
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare the efficacy and safety of two XW003 doses versus dulaglutide as add-on therapy to metformin in participants with type 2 diabetes mellitus (T2DM)

NCT ID: NCT05679466 Active, not recruiting - Clinical trials for Prevention of COVID-19 Caused by SARS-CoV-2

An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older

Start date: December 27, 2022
Phase: Early Phase 1
Study type: Interventional

Study Objective(s) To evaluate the safety, immunogenicity and protective efficacy of 1 dose of ReCOV in participants who have received 2 or 3 doses of inactivated SARS-CoV-2 vaccination in Chinese adults aged 18 years and older. Primary objective To demonstrate the safety within 30 days after booster dose. Secondary objective(s) To evaluate the immunogenicity after booster dose. To demonstrate the safety within 6 months after booster dose. To evaluate the protective efficacy of RT-PCR-confirmed SARS-CoV-2 infection and COVID-19 after booster dose. Indications:Prevention of COVID-19 caused by SARS-CoV-2 Population:Participants aged 18 years and older who completed 2 or 3 doses vaccination of inactivated COVID-19 vaccines and whose last dose was given 6-18 months, of which the elderly aged 60 years and older account for about 10% to 15%. Sample Size:Approximately 3,300 participants

NCT ID: NCT05679258 Active, not recruiting - Multiple Myeloma Clinical Trials

A Study to Compare the PK , Safety, Tolerability, and Immunogenicity of HLX15 With Daratumumab in Male Subjects

Start date: January 31, 2023
Phase: Phase 1
Study type: Interventional

Phase I Study to Compare the Pharmacokinetic Characteristics, Safety, Tolerability, and Immunogenicity (Randomized, Double-blind, Parallel Controlled) of HLX15 with Daratumumab Injection in Healthy Chinese Male Subjects