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NCT ID: NCT00548496 Terminated - Fracture Healing Clinical Trials

A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius

Start date: September 20, 2007
Phase: Phase 2
Study type: Interventional

This is a study designed to test the safety and effectiveness of SB-751689 in the treatment of a distal radius fracture in post-menopausal women and men in comparison to placebo to determine if healing time of the fracture can be decreased.

NCT ID: NCT00544271 Terminated - Tetanus Clinical Trials

Immunogenicity, Antibody Persistence and Safety of GSK Biologicals' DTPa (INFANRIX) and dTpa (BOOSTRIX) Vaccines.

Start date: May 2003
Phase: Phase 4
Study type: Interventional

To evaluate the immunogenicity, persistence of antibodies and reactogenicity of GSK Biologicals' DTPa (INFANRIX) and dTpa (BOOSTRIX), when administered to subjects 18-20 months old, compared with not giving a booster DTP vaccine at 18-20 months. Study double blinded for the two DTP vaccines and single blinded for the control arm.

NCT ID: NCT00543712 Terminated - Chondrosarcoma Clinical Trials

A Study of PRO95780 in Patients With Advanced Chondrosarcoma (APM4171g)

Start date: May 31, 2007
Phase: Phase 2
Study type: Interventional

This is a multicenter, open-label, Phase II trial designed to evaluate the efficacy and safety of PRO95780 when given as a single agent in patients with advanced chondrosarcoma. Up to 90 patients with confirmed chondrosarcoma will be enrolled.

NCT ID: NCT00534313 Terminated - Psoriatic Arthritis Clinical Trials

Safety and Efficacy of Abatacept Versus Placebo in Participants With Psoriatic Arthritis

Start date: November 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine an optimal abatacept dosing regimen for the treatment of active arthritis due to psoriatic arthritis in patients who have had a prior inadequate response to disease-modifying antirheumatic drugs, including methotrexate and tumor necrosis factor alpha-blockade compounds.

NCT ID: NCT00533351 Terminated - Neuralgia Clinical Trials

Safety and Efficacy of AGN201781 in Neuropathic Pain

Start date: March 2008
Phase: Phase 2
Study type: Interventional

This study will explore the safety and efficacy of AGN201781 in patients with postherpetic neuralgia or post-traumatic peripheral neuralgia

NCT ID: NCT00529503 Terminated - Clinical trials for Lymphoma, Non-Hodgkin

A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL

Start date: September 2007
Phase: Phase 2
Study type: Interventional

This is a randomized trial to estimate the activity of R-ICE plus SGN-40 vs. R-ICE plus placebo in patients with DLBCL. The study will assess safety and tolerability and will measure any additional clinical benefit observed in patients receiving SGN-40.

NCT ID: NCT00526071 Terminated - Fabry Disease Clinical Trials

Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study

Start date: September 17, 2007
Phase: Phase 2
Study type: Interventional

Study to evaluate the long-term safety, tolerability, and pharmacodynamics (PD) of migalastat hydrochloride (HCl) (migalastat) in participants with Fabry disease

NCT ID: NCT00523042 Terminated - Asthma Clinical Trials

Safety of Inhaled Preprandial Human Insulin in Subjects With Diabetes and Asthma

iINHALE 9
Start date: August 30, 2007
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe, Asia, Oceania and the United States of America (USA). This is a one-year clinical trial to compare the safety of inhaled preprandial human insulin to subcutaneous insulin aspart in subjects with type 1 or 2 diabetes and asthma.

NCT ID: NCT00522834 Terminated - Melanoma Clinical Trials

Elesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma

Start date: August 2007
Phase: Phase 3
Study type: Interventional

"Elesclomol (STA-4783), N-malonyl-bis (N'-methyl-N'-thiobenzoylhydrazide) is a new chemical entity with a novel structure. STA-4783 induces an oxidative stress response in cells. This response is characterized by increased production of gene families that protect against different cellular stresses, including excessive heat, the presence of reactive oxygen species such as oxygen radicals, or the presence of heavy metals. Subjects will participate in up to 2 weeks of screening during which time they will complete all screening procedures. Eligible subjects who have not received any prior cytotoxic chemotherapeutic agent for melanoma will be randomized in a 1:1 ratio to receive either STA-4783 213 mg/m2 in combination with paclitaxel 80 mg/m2 or paclitaxel 80 mg/m2 alone. One treatment cycle will consist of weekly treatments for 3 weeks, followed by a 1-week rest period. Cycles will be repeated every 4 weeks until disease progression. Tumor assessments will be performed every 8 weeks from the date of randomization or sooner if the Investigator suspects progression has occurred based on clinical signs and symptoms. "

NCT ID: NCT00520533 Terminated - Clinical trials for Renal Cell Carcinoma (RCC)

Study of Safety and Functional Imaging of cG250 and Sunitinib in Patients With Advanced Renal Cell Carcinoma

Start date: February 2008
Phase: Phase 1
Study type: Interventional

This clinical trial explores the safety, efficacy, and effects on functional imaging of cG250 monoclonal antibody (mAb) administered intravenously weekly in combination with daily oral sunitinib, in patients with advanced renal cell carcinoma.