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NCT ID: NCT04520412 Suspended - Alzheimer Disease Clinical Trials

A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease

GREEN MEMORY
Start date: October 27, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and efficacy of GV-971 in mild to moderate Alzheimer's disease.

NCT ID: NCT04166552 Suspended - Clinical trials for Diffuse Cutaneous Systemic Sclerosis

Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Diffuse Cutaneous Systemic Sclerosis

Start date: June 11, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of EHP-101 in adult subjects with diffuse cutaneous Systemic Sclerosis (dcSSc).

NCT ID: NCT03448926 Suspended - DCIS Clinical Trials

The PREDICT Registry for DCIS Patients With DCISionRT Testing

PREDICT
Start date: February 27, 2018
Phase:
Study type: Observational [Patient Registry]

This is a prospective cohort study for patients diagnosed with ductal carcinoma in situ (DCIS) of the breast. The primary objective of the study is to create a de-identified database of patients, test results, treatment decisions and outcomes that can be queried to determine the utility of the DCISionRT™ test in the diagnosis and treatment of ductal carcinoma in situ of the breast.

NCT ID: NCT03257215 Suspended - Atopic Dermatitis Clinical Trials

Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study

D-Vex
Start date: October 16, 2017
Phase: Phase 4
Study type: Interventional

Vitamin D is known to have a regulatory influence on both the immune system and skin barrier function. Studies in paediatric populations have found an inverse association of vitamin D levels and with both prevalence and severity of atopic dermatitis (AD). Trials of vitamin D as a treatment for AD are limited in number and size. There has never been a placebo-controlled randomised controlled trial of stoss high dose versus daily standard dose for the treatment of AD. Further, no trials have explored the presence of vitamin D pathway genes and response to treatment of AD. This pilot study will be used as a reference to determine outcomes and feasibility for undertaking a larger and more in depth definitive study.

NCT ID: NCT03175744 Suspended - Clinical trials for Critical Limb Ischemia

Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries

ILLUMENATE-BTK
Start date: May 24, 2017
Phase: N/A
Study type: Interventional

The purpose is to demonstrate the safety and effectiveness of the Stellarex DCB for the treatment of stenosis or occlusions of below-the-knee arteries.

NCT ID: NCT02156180 Suspended - Clinical trials for Oropharyngeal Squamous Cell Carcinoma

Identification of Breath Biomarkers in Head and Neck Squamous Cell Carcinoma

Start date: April 2014
Phase: N/A
Study type: Observational

In this study the Investigators aim to determine specific volatile compounds present in breath samples of patients with oral cavity or oropharyngeal squamous cell carcinoma before and after tumour resection or before and after chemotherapy +/- radiotherapy using gas chromotography-mass spectrometry. The Investigators hypothesize that study participants with a tumour will display a distinct set of volatile organic compounds than can serve as potential cancer biomarkers.

NCT ID: NCT01211691 Suspended - Clinical trials for Myelodysplastic Syndrome (MDS)

Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF)

Start date: September 2010
Phase: Phase 1/Phase 2
Study type: Interventional

This is a global, multicenter, open-label, repeat-dose, Phase 1/2 study consisting of a Dose Escalation Phase (Phase 1) and a Cohort Expansion Phase (Phase 2). In both phases, KB004 will be administered by IV infusion once weekly as part of a 21-day dosing cycle.

NCT ID: NCT00933348 Suspended - Pressure Ulcer Clinical Trials

Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine the safety and efficacy of the fruit-based product OPAL A for the treatment of chronic venous and pressure ulcers.