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NCT ID: NCT00391612 Active, not recruiting - Emphysema Clinical Trials

EASE Trial: Exhale Airway Stents for Emphysema

EASE
Start date: May 2006
Phase: Phase 3
Study type: Interventional

This is an international clinical research study evaluating the safety and effectiveness of a new procedure called airway bypass. The goal of this research is to see if airway bypass can relieve hyperinflation (overfilling) of the lungs, thereby improving lung function and reducing shortness of breath in patients with severe homogeneous (diffuse) emphysema. "EASE" stands for Exhale Airway Stents for Emphysema.

NCT ID: NCT00348738 Active, not recruiting - Cervix Cancer Clinical Trials

Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome

Start date: July 2000
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether an increase of blood haemoglobin levels through the substitution of erythropoietin during radiotherapy treatment of cervix cancer patients results in improvement for disease specific survival, tumor response and local control.

NCT ID: NCT00326079 Active, not recruiting - Open-Angle Glaucoma Clinical Trials

A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2

Start date: August 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma.

NCT ID: NCT00317408 Active, not recruiting - Lymphoma Clinical Trials

Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma

Start date: April 2004
Phase: N/A
Study type: Interventional

RATIONALE: Giving combination chemotherapy and total-body irradiation before a peripheral stem cell transplant that uses the patient's or a donor's stem cells, helps stop both the growth of cancer cells and the patient's immune system from rejecting the stem cells. When the stem cells are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Giving combination chemotherapy and total-body irradiation followed by a stem cell transplant may be an effective treatment for anaplastic large cell lymphoma. PURPOSE: This clinical trial is studying how well combination chemotherapy followed by stem cell transplant works in treating young patients with progressive or relapsed anaplastic large cell lymphoma.

NCT ID: NCT00302484 Active, not recruiting - Osteoporosis Clinical Trials

Use of Bisphosphonates in the Treatment of Osteopathy After Liver Transplantation

Start date: April 2002
Phase: N/A
Study type: Interventional

Patients with a terminal chronic liver disease have a disordered bone metabolism resulting in a higher risk of falling ill with osteoporosis. Although liver transplantation restores liver function, immunosuppressive therapy (especially corticosteroids) after transplantation increases again the risk of osteoporosis and bone fragility. Zoledronate, a bisphosphonate, slows down the destruction of bone. The purpose of this study is to determine whether bisphosphonates are effective in the prevention of osteoporosis following immunosuppressive therapy after liver transplantation.

NCT ID: NCT00261612 Active, not recruiting - Clinical trials for Lymphoma, Mantle-Cell

Bortezomib, Rituximab and Dexamethasone (BORID) for Relapsed/Refractory Mantle Cell Lymphoma

Start date: January 2005
Phase: Phase 2
Study type: Interventional

Mantle cell lymphoma (MCL) remains difficult to treat by standard treatment approaches. Novel drugs have shown promising results in early clinical evaluations. In the current trial, we investigate a combination of bortezomib (a proteasome inhibitor), rituximab (a monoclonal antibody), and dexamethasone in patients with MCL, who have already been pretreated by standard chemotherapy and show again signs of disease progression. The study objectives include remission rates, safety of this drug combination, and survival time.

NCT ID: NCT00222677 Active, not recruiting - Atherosclerosis Clinical Trials

Aspirin for the Prevention of Recurrent Venous Thromboembolism

Start date: May 2004
Phase: Phase 2/Phase 3
Study type: Interventional

To determine whether aspirin is more effective than placebo for the prevention of recurrent symptomatic venous thromboembolism when given for at least two years after the initial 6-12 month of oral anticoagulant therapy in patients with idiopathic venous thromboembolism

NCT ID: NCT00166257 Active, not recruiting - Clinical trials for Heart Septal Defects, Atrial

PC-Trial: Patent Foramen Ovale and Cryptogenic Embolism

Start date: February 2000
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare two treatments strategies to prevent further attacks in patients who have suffered an stroke or occlusion of a major artery with no obvious reason other than a persistent small opening between the upper heart chambers

NCT ID: NCT00156741 Active, not recruiting - Clinical trials for Bradycardia; Sick Sinus Syndrome, AV Block

Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.

Start date: April 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to provide evidence that the Refined Ventricular Pacing Algorithm leads to clinically relevant reduction (at least 50% reduction) of the incidence of ventricular pacing.

NCT ID: NCT00142259 Active, not recruiting - Dystonia Clinical Trials

Efficacy and Safety of DBS of the GPi in Patients With Primary Generalized and Segmental Dystonia

Start date: October 2002
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of bilateral deep brain stimulation of the internal globus pallidus for treating idiopathic generalized or severe segmental dystonia.