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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01240174
Other study ID # 2010P001247
Secondary ID
Status Completed
Phase N/A
First received November 10, 2010
Last updated January 30, 2017
Start date March 2011
Est. completion date July 2014

Study information

Verified date January 2017
Source Brigham and Women's Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Studies show, guidelines state, and performance measures assert that antibiotic prescribing for uncomplicated acute bronchitis is inappropriate. However, clinicians prescribe antimicrobials in over 60% of the 22.5 million acute bronchitis visits in the United States each year. Previous successful interventions have only reduced the antimicrobial prescribing rate to 40% or 50%. It is unknown if the antimicrobial prescribing rate for acute bronchitis can be brought to near zero percent in actual practice while maintaining patient safety and satisfaction. The goal of this study is to develop an Electronic Health Record (EHR)-integrated algorithm for the diagnosis and treatment of adults with acute bronchitis with a goal of reducing the antibiotic prescribing rate to near zero percent.


Description:

We will use a multi-modal implementation - including computerized decision support, reporting tools, and clinician feedback - and quality improvement techniques to ensure adherence to the algorithm and reduce the antimicrobial prescribing rate to near zero percent. The duration of the intervention will be 4 years.


Recruitment information / eligibility

Status Completed
Enrollment 400
Est. completion date July 2014
Est. primary completion date June 2014
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 64 Years
Eligibility Inclusion Criteria:

- first visit in 30 days, age 18-64, has a cough of less than 3 weeks duration

Exclusion Criteria:

- infiltrate on chest x-ray, has chronic lung disease

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Demonstration of near zero antibiotic prescribing for patients with acute bronchitis
A controlled, continuously-monitored, implementation of an EHR-integrated diagnosis and treatment algorithm for acute bronchitis in a large, diverse primary care practice.

Locations

Country Name City State
United States Brigham and Women's Hospital Jen Center for Primary Care Boston Massachusetts

Sponsors (2)

Lead Sponsor Collaborator
Brigham and Women's Hospital Agency for Healthcare Research and Quality (AHRQ)

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary Antibiotic prescribing rate The antibiotic prescribing rate for patients with acute bronchitis 30 days
Secondary Patient symptoms 21 days
Secondary Patient satisfaction 21 days
Secondary Patient safety 30 days
Secondary Healthcare costs 30 days
Secondary The capture and description of the components that had the greatest effect on the antimicrobial prescribing rate 3 years
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