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Cough clinical trials

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NCT ID: NCT00173225 Recruiting - Asthma Clinical Trials

Sputum and Plasma Levels of Nociceptin and Substance P in Patients With Asthma, COPD and Chronic Cough

Start date: June 2005
Phase: N/A
Study type: Observational

The aims of this study are to investigate the association between sputum and plasma levels of nociceptin and substance P with cough severity and airway hyperreactivity in patients with asthma, COPD and chronic cough.

NCT ID: NCT00131157 Active, not recruiting - Asthma Clinical Trials

Evaluation of Spirometry Expert Support in General Practice

Start date: January 2003
Phase: N/A
Study type: Interventional

More and more general practitioners (GPs) use spirometry in their practices. At this time, there is sufficient reason to presume that, after a single postgraduate training program without any further support, most GPs have insufficient knowledge and ability to assure valid interpretation of their spirometry tests. Therefore, some kind of continuous diagnostic support with regard to spirometry interpretation by GPs is advisable. The aim of the present study is to assess whether implementation of spirometry expert support (either by a computerised expert system or a working agreement between general practitioners and respiratory consultants with respect to spirometry interpretation) causes changes in diagnosing and appropriateness and efficiency of medical care in subjects with chronic respiratory morbidity managed in general practice.

NCT ID: NCT00127686 Completed - Clinical trials for Respiratory Tract Infections

Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep

Start date: September 2005
Phase: Phase 1
Study type: Interventional

Cough is the most common reason for an acute care doctor's visit in the United States. Cough can affect sleep for both coughing children and their parents. The American Academy of Pediatrics does not endorse the use of dextromethorphan (DM), the most common over-the-counter (OTC) cough medication because of a lack of efficacy data and some potential for toxicity, particularly when taken in excess. In fact, DM has previously been shown to be no better than a placebo for cough in children. Therefore, alternative, therapeutic agents are needed. Honey anecdotally provides relief for symptoms due to upper respiratory tract infection (URI). This study seeks to use a survey to evaluate whether a single dose of honey and/or DM is better than no treatment at all for controlling nocturnal cough in children with URI and the effect of the treatments on sleep quality for coughing children and their parents. A single dose of honey or DM will be superior to no treatment for control of nocturnal cough due to upper URI as rated by both parents and children and will improve the sleep quality for those children and parents. Compared to DM, honey will be superior for controlling nocturnal cough due to upper URI (also based on child and parental report).

NCT ID: NCT00116337 Completed - Clinical trials for Spinal Cord Injuries

Spinal Cord Stimulation to Restore Cough

Start date: September 30, 2004
Phase: N/A
Study type: Interventional

The purpose of this trial is to determine the efficacy of spinal cord stimulation to produce an effective cough in patients with spinal cord injuries.

NCT ID: NCT00044317 Completed - Cough Clinical Trials

Health Effects of Particulate Acids in Late Adolescence

Start date: n/a
Phase: N/A
Study type: Observational

This study was designed to follow a group of adolescents who were previously examined by questionnaire and pulmonary function tests when they were aged 8-10 years old. Approximately 50% of the population in 10 towns were seen again at age 17-18. Questionnaires and pulmonary function were repeated. The hypotheses being tested related to whether the previously seen levels of pulmonary function that were related to pollution levels in the towns persisted as the lungs of these children grew and whether dietary antioxidants influences level of attained pulmonary function.