Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency

Status Not yet recruiting

Clinical Trial Summary

This single-centre cross-sectional study aims to ascertain the impact of dyslipidemia on long-term graft patency after coronary artery bypass grafting (CABG).

Clinical Trial Description

All consecutive patients who underwent CABG from 1st January 2007 to 31st December 2008 at the Prince of Wales Hospital were eligible for entry. Graft patency will be determined by computed tomography coronary angiogram. The severity of stenosis will be classified by the Fitzgibbon classification system. The levels of individual lipid profile subcomponents, namely LDL-C, high-density lipoprotein cholesterol (HDL-C), total cholesterol and triglycerides (TG) will be obtained. A plot of lipid profile subcomponent measurements against time will be compiled and the area under the curve is calculated to estimate gross exposure after CABG. Average lipid exposure is calculated by dividing the gross exposure by the number of days lapsed between the first and last lipid profile measurements. The association between average cholesterol target attainment and graft patency will then be determined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05393882
Study type	Observational [Patient Registry]
Source	Chinese University of Hong Kong
Contact	Randolph HL Wong, FRCS
Phone	35052629
Email	wonhl1@surgery.cuhk.edu.hk
Status	Not yet recruiting
Phase
Start date	September 1, 2024
Completion date	December 31, 2027

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