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Coronary Bypass Graft Stenosis clinical trials

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NCT ID: NCT05430568 Not yet recruiting - Clinical trials for Valvular Heart Disease

Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery

Start date: August 1, 2022
Phase:
Study type: Observational

Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases. Studies have shown that, as compared to conventional sternotomy, patients underwent robot-assisted bypass grafting or valvuloplasty had less post-operation pain, blood transfusion volume during operation, re-operation rate, post-operation stroke rate and length of hospitalization. However, most studies focused on the comparison of complications of different procedures, and the investigation of cardiopulmonary function recovery is still lacking. Thus our study is to compare the functional outcomes between patients that undergo different surgical procedures.

NCT ID: NCT05393882 Not yet recruiting - Clinical trials for Coronary Artery Disease

Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency

Start date: September 1, 2024
Phase:
Study type: Observational [Patient Registry]

This single-centre cross-sectional study aims to ascertain the impact of dyslipidemia on long-term graft patency after coronary artery bypass grafting (CABG).

NCT ID: NCT05129228 Recruiting - Clinical trials for Coronary Bypass Graft Stenosis

Optical Coherence Tomography of the Saphenous Vein Graft

OCTOCAB
Start date: April 4, 2022
Phase: N/A
Study type: Interventional

OCTOCAB is a prospective, randomized (1:1), single-center trial. The purpose of this study is to determine whether intravascular optical coherence tomography (OCT) guided saphenous vein grafting in coronary artery bypass surgery will reduce the rate of early vein graft failure (VGF).

NCT ID: NCT03734159 Completed - Clinical trials for Coronary Bypass Graft Stenosis

The Benefit of Local Anesthesia at the Sternum in Patients With Coronary Surgery

PARA
Start date: December 13, 2018
Phase: Phase 4
Study type: Interventional

Patients undergoing coronary artery bypass grafting are at risk for perioperative myocardial ischemia. Episodes of tachycardia and hypertension, which are associated with an increase in myocardial oxygen consumption, are predictive events of these ischemia. During cardiac surgery by sternotomy, some maneuvers, e.g. intubation, skin incision, sternotomy and cannulation, may be associated with tachycardia and/or increases in blood pressure despite an adequate level of anesthesia. Usually these episodes are controlled by the administration of a high-dose of anesthetic agents. The parasternal block, by bolus or continuous infusion through a single catheter, showed its effectiveness on postoperative pain after sternotomy. It allows a blocking of anterior branches of intercostal nerves at the lateral edge of the sternum; branches in charge of innervation of the sternum and the overlying skin surface. The preoperative parasternal block, once general anesthesia performed, could provide an effective level of locoregional anesthesia of the chest wall, thus limiting the occurrence of episodes of tachycardia and / or hypertension without having to resort to massive doses of anesthetic agents during sternotomy in patients undergoing coronary bypass surgery.

NCT ID: NCT02814084 Completed - Cardiac Event Clinical Trials

Prevena Incision Management

Prevena
Start date: September 13, 2016
Phase: N/A
Study type: Interventional

The question this research project wants to explore is whether using the Prevena Incision Management System (Prevena) will improve sternal wound edge oxygenation in patients undergoing Coronary Artery bypass surgery with Bilateral Internal Mammary Artery grafts.

NCT ID: NCT01186198 Completed - Clinical trials for Ischemic Heart Disease

A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions

CROSS
Start date: August 12, 2010
Phase:
Study type: Observational

This is a prospective, single-arm, open-label, multi-center, observational study to assess the acute safety and efficacy of MINI TREK RX 1.20 mm for enlarging coronary luminal diameter during percutaneous coronary intervention (PCI) procedures in subjects with ischemic heart disease due to stenotic lesions.