HanYang University Medical Center (HYUMC) Registry

Coronary Artery Disease Clinical Trial

— HYUMC  

Official title:

HanYang University Medical Center (HYUMC) PCI Registry

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05935397
• Other study ID #: HYUMC
• Status: Recruiting
• Start date: January 1, 2012
• Est. completion date: December 31, 2025

Study information

• Verified date: June 2023
• Source: Hanyang University Seoul Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The HYUMC registry is a two-center, real-world registry of percutaneous coronary intervention in patients with coronary artery disease. From January 2012, PCI-treated patients from Hanyang University Seoul Hospitals and Hanyang University Guri Hospitals were enrolled in this registry.

The aim of this registry is to examine the long-term clinical outcomes and identify predictors of adverse outcomes following percutaneous coronary intervention conducted at academic hospitals.

Description:

In the HYUMC registry, the researchers have gathered and assessed various demographic, laboratory, echocardiographic, and angiographic measurements (both on-admission and during follow-up), as well as conducted questionnaires among patients who underwent percutaneous coronary intervention. The primary focus of this registry is to examine the effects of these parameters on long-term clinical outcomes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 5000
• Est. completion date: December 31, 2025
• Est. primary completion date: December 31, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 19 Years and older

Eligibility

Inclusion Criteria:

Consecutive patients with CAD who underwent PCI one or more drug eluting stent (DES) with from 2012 at the Division of Cardiology of Hanyang University Seoul Hospital and Hanyang University Guri Hospital, Korea.

Exclusion Criteria:

• second or subsequent hospitalization records of patients with multiple admissions

• patients who died during index hospitalization

• patients who treated with first-generation drug eluting stent

• patients with an outpatient follow-up record of less than 6 months

• patients with insufficient medical records.

Related Conditions & MeSH terms

• Blood Pressure
• Coronary Artery Disease
• Coronary Artery Stenosis
• Coronary Stenosis

Intervention

Device:
• percutaneous coronary intervention
patients with CAD undergoing PCI with second generation DES

Locations

Country	Name	City	State
Korea, Republic of	Hanyang University Guri Hospital	Guri
Korea, Republic of	Hanyang University Seoul Hospital	Seoul
Korea, Republic of	Young-Hyo Lim	Seoul

Sponsors (2)

Lead Sponsor	Collaborator
Hanyang University Seoul Hospital	Hanyang University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MACCE (major adverse cardiac and cerebrovascular event)	the composite of all-cause death, myocardial infarction, stroke, or any revascularization	10-year
Secondary	All-cause death	death from any cause	10-year
Secondary	Myocardial infarction,	presence of clinical symptoms with the presence of electrocardiographic changes, or imaging evidence of new loss of viable myocardium or new regional wall motion abnormalities, in conjunction with elevated levels of cardiac biomarker above the 99th percentile upper reference limit	10-year
Secondary	Stroke	neurological deficit resulting from acute focal damage to the central nervous system due to a vascular cause, requiring hospitalization, and confirmed by a neurologist through imaging findings	10-year
Secondary	Any revascularization	PCI or coronary artery bypass surgery on either target or nontarget vessels	10-year