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Clinical Trial Summary

This study aims to compare vessel response and clinical outcomes of a biodegradable-polymer, ultra-thin strut, drug-eluting stent (Orsiro, Biotronik) and a durable-polymer, thin-strut, drug-eluting stent (Xience, Abbott) for the treatment of coronary bifurcation lesions with two-stent double-kissing crush technique. How the differences in stent platforms affect vessel healing process will be examined by optical coherence tomography.


Clinical Trial Description

Patients with true coronary bifurcation lesions (Medina [1, 1, 1] or [0, 1, 1]) will be enrolled and randomized to undergo two-stent double kissing crush technique with Orsiro or Xience. Pre-intervention and post-stenting optical coherence tomography will be performed during the index procedure. Another parallel prospective registry will enroll patients with bifurcation lesions treated with provisional one-stent strategy. All subjects will receive coronary angiography and optical coherence tomography follow-up at 3 and 12 months. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05200637
Study type Interventional
Source Chang Gung Memorial Hospital
Contact Ying-Chang Tung, MD
Phone 886-3-3281200
Email n12374@cgmh.org.tw
Status Not yet recruiting
Phase N/A
Start date February 1, 2022
Completion date December 31, 2024

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