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NCT01517425 Clinical Trial

Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells

Coronary Artery Disease Clinical Trial

— iPSC  

Official title:
Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT01517425
Other study ID # 11-5676
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date November 2012
Est. completion date July 2030

Study information
Verified date March 2021
Source Scripps Translational Science Institute
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This research is being done to understand how changes in DNA may put people at risk for developing coronary artery disease. Stem cells will be made using cells from blood and/or skin biopsy samples. We are trying to understand which specific changes in DNA negatively impact a person's health.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 200
Est. completion date July 2030
Est. primary completion date July 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Cases: 1. Previously enrolled in the CAD module of the Genebank at Scripps Clinic Registry 2. Eligible to have their blood drawn 3. Be reliable, cooperative and willing to comply with all protocol-specified procedures 4. Able to understand and grant informed consent Controls: 1. Previously enrolled in the Healthy Elderly Active Longevity (HEAL) Cohort 2. Eligible to have their blood drawn 3. Be reliable, cooperative and willing to comply with all protocol-specified procedures 4. Able to understand and grant informed consent Exclusion Criteria: 1. Unwilling or unable to grant informed consent. 2. Have a significant medical condition that in the Investigator's opinion may interfere with subject's study participation.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Scripps Translational Science Institute La Jolla California

Sponsors (1)
Lead Sponsor Collaborator
Scripps Translational Science Institute

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary iPSC development Develop methods of iPSC generation from patients with genomic risk. five years
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