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CAlcified Lesion Intervention Planning Steered by OCT. — CALIPSO  

Coronary Artery Calcification Clinical Trial

Official title:
CAlcified Lesion Intervention Planning Steered by OCT.

Clinical Trial Summary

Calcified lesions are very frequent among coronary artery disease stenotic lesions. The prevalence of calcifications ranges from 30 to 40% (by angiography evaluation) but is higher when analyzed by intra coronary imaging. Calcified lesions are very frequent among coronary artery disease stenotic lesions. The prevalence of calcifications ranges from 30 to 40% (by angiography evaluation) but is higher when analyzed by intra coronary imaging. The presence of calcifications increases the risk of adverse evolution after PCI , including stent restenosis, thrombosis and need for repeat revascularisation. Specific and appropriate tools can be used for calcified lesions management , including high pressure non compliant balloons, intravascular lithotripsy and rotablator. Intra vascular OCT has a high sensitivity and specificity for calcium detection among coronary artery lesions. Compared to IVUS, OCT allows a better quantification of calcium sheets (depth extension ) . Several intra coronary imaging based calcified lesions management algorithms have been proposed , but none have been validated in clinical practice.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05301218
Study type Interventional
Source Institut Mutualiste Montsouris
Contact Nicolas Amabile, MD PhD
Phone 0156616983
Email nicolas.amabile@imm.fr
Status Recruiting
Phase N/A
Start date December 15, 2021
Completion date December 15, 2023
View Details
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