CAlcified Lesion Intervention Planning Steered by OCT. — CALIPSO  

Coronary Artery Calcification Clinical Trial

Official title: CAlcified Lesion Intervention Planning Steered by OCT.

Status Recruiting

Clinical Trial Summary

Calcified lesions are very frequent among coronary artery disease stenotic lesions. The prevalence of calcifications ranges from 30 to 40% (by angiography evaluation) but is higher when analyzed by intra coronary imaging. Calcified lesions are very frequent among coronary artery disease stenotic lesions. The prevalence of calcifications ranges from 30 to 40% (by angiography evaluation) but is higher when analyzed by intra coronary imaging. The presence of calcifications increases the risk of adverse evolution after PCI , including stent restenosis, thrombosis and need for repeat revascularisation. Specific and appropriate tools can be used for calcified lesions management , including high pressure non compliant balloons, intravascular lithotripsy and rotablator. Intra vascular OCT has a high sensitivity and specificity for calcium detection among coronary artery lesions. Compared to IVUS, OCT allows a better quantification of calcium sheets (depth extension ) . Several intra coronary imaging based calcified lesions management algorithms have been proposed , but none have been validated in clinical practice.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Angioplasty
• Calcinosis
• Coronary Artery Calcification

• NCT number: NCT05301218
• Study type: Interventional
• Source: Institut Mutualiste Montsouris
• Contact: Nicolas Amabile, MD PhD
• Phone: 0156616983
• Email: nicolas.amabile@imm.fr
• Status: Recruiting
• Phase: N/A
• Start date: December 15, 2021
• Completion date: December 15, 2023