Coronary Artery Atherosclerosis Clinical Trial
Official title:
Effect of Preoperative Imaging of the Ascending Aorta With Modified Transoesophageal Echocardiography on New Dw-MRI Lesions After Cardiac Surgery
Patients undergoing cardiac surgery frequently develop neurologic complications, ranging
from subtle cognitive changes to evident confusion, delirium, and stroke. This continuum of
complications is commonly caused by embolization in the brain due to manipulation of
atherosclerotic parts of the aorta ascendens (AA) during surgery. Timely detection of AA
atherosclerosis before surgery enables the surgeon to consider changes of the surgical plan,
to reduce the risk of embolization and thus subsequent neurologic complications.
Various methods exist to visualize the AA to detect atherosclerosis. Epiaortic ultrasound
scanning has become the gold standard, but is seldom used as it interferes often with
surgical plan and can only be used after sternotomy. Transesophageal echocardiography (TEE)
is a widely used imaging method permitting evaluation of the aorta preoperatively, but
assessment of distal AA is hampered by interposition of air-filled trachea between esophagus
and AA. The A-View® (Aortic-view) method, a modification of conventional TEE using a
fluidfilled balloon, overcomes this limitation. The safety and diagnostic accuracy of the
A-View® have successfully been shown in previous studies. The hypothesis of this study is
that the use of A-View will reduce cerebral embolization secondary to a change of surgical
technique.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Diagnostic
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04010955 -
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