COPD Clinical Trial
— SADOfficial title:
The SAD Study - SLEEP, ANXIETY & DEPRESSION Study A Prospective Cohort Study
Verified date | November 2013 |
Source | The Queen Elizabeth Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Australia: Human Research Ethics Committee |
Study type | Interventional |
The prevalence of anxiety and depression in our OSA population is more than in COPD and the
general population of North West Adelaide. (principal hypothesis).
CPAP therapy in OSA population produces a positive effect on the anxiety and depression
scale.
The Investigators intend to study the prevalence of anxiety and depression in patients with
sleep disorders in comparison to patients with COPD and subsequently, to assess whether CPAP
has a role in controlling anxiety and depression in depressed and anxious patients with
sleep apnoea.
This is a two phase study, in first phase; investigator will assess the prevalence of
anxiety and depression, in a population with sleep disorders to check whether it is
different to the prevalence in the COPD population. The prevalence of depression in Sleep
Disorder population will also be compared with the Adelaide North Western general
population, which was reported in The North West Adelaide Health Study. According to this
epidemiological survey, which was conducted from 2008 to 2010, the prevalence of depression
in Adelaide North Western general population was 20%.During the second phase of the study
investigator will evaluate the effect of CPAP on anxiety and depression scores in the
depressed and anxious patients with sleep apnoea by comparing the pre and post CPAP anxiety
and depression status. The Hospital Anxiety and Depression (HAD) scale will be used to
assess Anxiety and Depression, which is a well-documented tool for assessing symptoms of
anxiety and depression in patients with somatic diseases.
Status | Not yet recruiting |
Enrollment | 500 |
Est. completion date | March 2015 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 75 Years |
Eligibility |
Inclusion Criteria: - Patients attending the Respiratory and Sleep Outpatient Clinics at LMH and TQEH with OSA or COPD - Aged over 18 years Exclusion Criteria: - Unwilling or unable to give informed written consent |
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research
Country | Name | City | State |
---|---|---|---|
Australia | The Queen Elizabeth Hospital | Adelaide | South Australia |
Lead Sponsor | Collaborator |
---|---|
The Queen Elizabeth Hospital | Lyell McEwin Hospital |
Australia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To establish the prevalence of anxiety and depression in patients with sleep disorders and compare how this prevalence differs from its prevalence in COPD and in the general population. | 24weeks | No | |
Secondary | To evaluate whether treatment with CPAP improves anxiety and depression symptoms (HAD scale) at 3 and 12 months in OSA patients with anxiety and depression. | 24 months | No |
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