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NCT ID: NCT04969146 Suspended - Intervention Clinical Trials

A Sleep Intervention for Cancer Patients and Their Caregivers

Start date: August 16, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to design and test a dyadic sleep intervention for patients diagnosed with cancer and their intimate partner.

NCT ID: NCT04557566 Completed - Control Clinical Trials

ED Recovery Course Online RCT

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to examine whether the Eat Breathe Thrive (EBT) Yoga for Eating Disorder Recovery online course is effective in supporting eating disorder recovery.

NCT ID: NCT04103957 Recruiting - Stroke Clinical Trials

Exploring the Effect of Visual Feedback on Motion Trajectory in a Virtual Reality Environment.

Start date: April 10, 2020
Phase:
Study type: Observational

The rehabilitation intensity and frequency of upper extremities of stroke patients is insufficient. Virtual reality technique may solved this problem. The investigators want to build up the motion trajectory system by head-mounted display virtual reality technique, and to explore the effect of visual feedback on motion trajectory in a virtual reality environment.

NCT ID: NCT03912597 Recruiting - Behavior Clinical Trials

VR-assisted Curriculum on Depression for Stigma Reduction

Start date: September 19, 2018
Phase: N/A
Study type: Interventional

Two randomised controlled trials will be conducted to evaluate a virtual reality (VR) simulation designed to reduce stigma against depression. Qualitative interviews will also be carried out to evaluate the VR simulation.

NCT ID: NCT03602248 Completed - Control Clinical Trials

Speed Endurance Training, Muscle Damage and Performance in Soccer Players

SPENSER
Start date: May 8, 2018
Phase: N/A
Study type: Interventional

Soccer is an intermittent sport in which the aerobic and anaerobic capacity of the players are both very important. Elite football players perform an average of 150-250 short and intense movements during a match, demonstrating the significant contribution of the anaerobic energy system. Speed endurance training consists a tool to enhance the performance of aerobic and anaerobic system. This training includes actions such as sprinting, changes of direction, accelerations, decelerations, jumps and shooting, characterized by a strong eccentric component. Eccentric actions are associated with exercise induced muscle damage (EIMD). Nevertheless, to date, EIMD responses following a session of speed endurance training have not yet been investigated. Therefore, the aim of the present study is to examine the EIMD responses and changes on performance and neuromuscular fatigue indices after two different speed endurance training protocols.

NCT ID: NCT03476200 Completed - Control Clinical Trials

Efficacy of Cognitive Behavioral Therapy and Hair Cortisol Concentration

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Stress is considered as a risk factor for physical and mental health. For this reason, interventional programs focused on stress management have been developed. These programs have proven to be efficacious modifying emotional variables and psychopathological symptoms. However, there are no studies showing how these interventions modify objective measures of stress. For example, measures reflecting Hipotalamic-Pituitary-Adrenal (HPA) axis activity, the main system involved in the stress response. The activity of HPA axis is also altered by illness and psychopathology. Hair cortisol technique allows for changes assessment of HPA axis activity during months. Therefore, hair cortisol may be considered as an useful tool to measure changes of emotional variables related to stress in the long term. This measure of change over time of HPA axis activation together with related emotional variables assessment could be useful to evaluate the efficacy of interventional programs. For this reason, the aim of this research is to assess the effects of a cognitive-behavioral treatment (CBT) on perceived stress, resilience, worries, psychopathology and HPA axis activity through hair cortisol analysis.

NCT ID: NCT03238300 Completed - Alcohol Drinking Clinical Trials

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

Start date: October 16, 2017
Phase: Phase 2
Study type: Interventional

This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).

NCT ID: NCT03216213 Completed - Behavior Clinical Trials

Evaluating Attitudes Towards Organ Donation in Singapore

Start date: September 27, 2018
Phase: N/A
Study type: Interventional

One survey is conducted. Exploring the effect of different messages on family members' decision making on organ donation.

NCT ID: NCT02128737 Completed - Control Clinical Trials

Neurobehavioral Effects of Partial Sleep Deprivation

Start date: December 2009
Phase: N/A
Study type: Interventional

This project continues an innovative line of research on how to optimally use sleep as an intervention to promote cognitive recovery from, and resistance to, the neurobehavioral risks posed by chronic partial sleep deprivation. Chronic insufficient sleep is estimated to affect at least 20% of adults. It can result from medical conditions and sleep disorders, as well as work demands, and social or domestic responsibilities. It is associated with significant clinical morbidity, and directly causes errors and accidents that are due to its adverse neurobehavioral effects on alertness, mood, and cognitive functions. In seminal experiments conducted under this grant, we showed that the neurobehavioral effects of chronic sleep restriction accumulate to severe levels in a few days, without the full awareness of the affected individuals, and that recovery from chronic sleep restriction requires more sleep than previously assumed. We also discovered that recovery from chronic sleep was illusory, because it masked a heightened neurobehavioral vulnerability to even a single post-recovery night of sleep restriction. The implications of these findings are that apparent recovery from chronic sleep restriction masks a more severe cognitive response to subsequent sleep restriction suggesting that there are longer time constants in the brain for neurobehavioral recovery from chronic sleep restriction. In light of this finding, we now seek to determine whether additional nights of extended recovery sleep will reduce the heightened vulnerability induced by prior exposure to sleep restriction. A total of 87 healthy adults (ages 21-50) will be studied in the laboratory during a 17-night (N=63) and a 19-night (N=24) protocol evaluating cognitive, psychological and physiological responses to varying recovery days between two sleep-restriction periods. The results will establish the number of nights of recovery sleep needed to prevent accelerated deterioration during a subsequent period of sleep restriction. The findings will advance theoretical understanding of sleep homeostasis and its relationship to cognitive functions, as well as inform theories of sleep need, and have substantial implications for sleep biology, for the treatment of clinical disorders that regularly disrupt sleep, and for managing lifestyle factors that frequently restrict sleep.

NCT ID: NCT02082145 Completed - Control Clinical Trials

Electrical Stimulation in Diabetic Peripheral Neuropathy

NERVES
Start date: July 2014
Phase: N/A
Study type: Interventional

To assess the effect of the device on the progression of diabetic peripheral neuropathy