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Contraception clinical trials

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NCT ID: NCT00161447 Completed - Contraception Clinical Trials

Male Hormonal Contraceptive Development-ACY-5

ACY-5
Start date: May 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research study is to help in the development of male contraception (birth control).

NCT ID: NCT00161421 Completed - Contraception Clinical Trials

Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the how the body absorbs and processes new forms of oral testosterone. Information gained during the study may help develop better forms of testosterone therapy in the future. We will be administering three drugs. Dutasteride is FDA approved to treat prostate enlargement. Lupron is approved for treatment of prostate cancer. Testosterone is approved for treatment of testicular insufficiency. They are being used in this study for "off-label" research purposes. This study will allow us to find out the effect of food on two formulations of testosterone taken by mouth, and the relative effect of food on testosterone absorption. Information from this study may be useful in treatment of men with low testosterone levels and the development of a male hormonal contraceptive.

NCT ID: NCT00156650 Completed - Contraception Clinical Trials

Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum

IHOP-5
Start date: December 2004
Phase: Phase 1/Phase 2
Study type: Interventional

This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary. The purpose of this added procedure (Testicular Aspiration-HOP 3) is to determine the amount of testosterone (male hormone) in the testes of men who are on a male contraceptive regimen.

NCT ID: NCT00139685 Completed - Contraception Clinical Trials

Depo-Provera: Bone Mineral Density and Total Body Calcium in Adolescent DP150CI Users and Non-Hormonal Contraception

Start date: April 1998
Phase: Phase 4
Study type: Interventional

To evaluate and compare Bone Mineral Density (BMD) in adolescent Depo-Provera Contraceptive Injection (DP150CI) users during depo medroxyprogesterone acetate (DMPA) therapy and following discontinuation of DMPA. Another group electing non-hormonal contraception or abstinence will be recruited as a reference population, across all study sites. The primary variable is BMD, measured by Dual Energy X-ray Absorptiometry (DXA). Secondary variables are: Total Body Composition& Total Body Calcium (TBC), measured by Dual Energy X-ray Absorptiometry (DXA), and surrogate biologic BMD markers. Safety will be evaluated by adverse event reporting, laboratory evaluations, pregnancies, weight and vital signs.

NCT ID: NCT00131885 Completed - Contraception Clinical Trials

Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel

Start date: August 2005
Phase: Phase 4
Study type: Interventional

This study will determine the effects of St. John's wort, a common herbal remedy, on metabolism of the female contraceptive hormone levonorgestrel.

NCT ID: NCT00068848 Completed - Pregnancy Clinical Trials

Quick Start Approach to Birth Control Pills

Start date: February 2003
Phase: Phase 4
Study type: Interventional

Women who choose to take birth control pills are currently instructed to begin taking the pills at the end of a menstrual cycle. This creates a window of time between when the woman is given the pills and when she begins taking them. Some women fail to begin taking the pills, placing them at increased risk of pregnancy. This study will evaluate a new approach to beginning birth control pills. Women will take the first pill in the doctor’s office rather than waiting until the next menstrual cycle.

NCT ID: NCT00067509 Completed - Pregnancy Clinical Trials

Emergency Contraception (ECP): Reducing Unintended Pregnancies

Start date: June 2001
Phase: Phase 4
Study type: Interventional

Emergency contraception is a method of birth control that can be used up to three days after sexual intercourse. Emergency contraceptive pills (ECPs) can be given to a woman before she needs them (advance provision) or when she needs them (emergency provision). This study will compare these two methods of providing ECPs.

NCT ID: NCT00065871 Active, not recruiting - Contraception Clinical Trials

The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies

Start date: June 2003
Phase: N/A
Study type: Interventional

Hormonal birth control methods include birth control pills, patches, and vaginal rings; they are normally available only with a doctor’s prescription. This study will evaluate a program designed to increase the availability of birth control by allowing pharmacists to give women hormonal birth control without a doctor’s prescription. Under this program, pharmacists will evaluate women who want to use birth control according to specific guidelines created by doctors. If a woman meets the criteria in the guidelines, a pharmacist could then give her the appropriate form of hormonal birth control.

NCT ID: NCT00026013 Completed - Contraception Clinical Trials

Effects of St. John's Wort on the Effectiveness of Oral Contraceptives

Start date: January 2002
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives as well, it may increase the risk of contraceptive failure and unintended pregnancy. Study participants will be evaluated for risk of ovulation on oral contraceptives before and during simultaneous therapy with St. John's Wort.