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Contraception clinical trials

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NCT ID: NCT00456924 Completed - Contraception Clinical Trials

Low Dose Continuous Administration of the Progesterone Receptor Modulator VA2914

Start date: January 2004
Phase: Phase 2
Study type: Interventional

The purpose of the present study is to evaluate continuous administration of low doses of VA2914 for potential contraceptive activity and effects on the menstrual cycle and steroid hormone parameters.

NCT ID: NCT00455156 Completed - Contraception Clinical Trials

Study of the Safety, Efficacy and Cycle Control of a Contraceptive Vaginal Ring

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the one-year data on the contraceptive efficacy and safety of the 150/15 NES/EE CVR as the basis for regulatory approvals of this CVR as a new delivery system for contraception.

NCT ID: NCT00447863 Withdrawn - Contraception Clinical Trials

Study Evaluating the Bioequivalence of Levonorgestrel/Ethinyl Estradiol Combinations in Cycling Women

Start date: August 2007
Phase: Phase 1
Study type: Interventional

Levonorgestrel/ethinyl estradiol (LNG/EE) is an investigational drug that is being developed as an oral contraceptive (birth control pill). The purpose of this trial is to compare different preparations of LNG/EE by assessing the way they are absorbed into the blood.

NCT ID: NCT00439972 Unknown status - Contraception Clinical Trials

Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity

Start date: February 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the effects of oral versus patch administration of hormonal contraception on hormone sensitive proteins such as lipoproteins, clotting factors and inflammatory proteins as well as blood sugar and insulin levels, antioxidant status and flow-mediated dilation of arm and forearm vessels. The hypothesis is that oral administration of contraceptive hormones will result in higher plasma levels of estrogen sensitive proteins originating from the liver while patch administration of contraceptive hormones will result in greater systemic effects of estrogen on vascular reactivity and antioxidant status.

NCT ID: NCT00436306 Completed - Pregnancy Clinical Trials

Stage Matched Intervention to Increase Dual Method Use

PROTECT
Start date: October 1999
Phase: Phase 4
Study type: Interventional

The primary purpose of Project PROTECT was to evaluate two different intervention approaches that encourage young women to use dual methods of contraception. The individualized intervention is a computer assisted, fully-tailored, interactive intervention based on the transtheoretical model of behavior change. This intervention was compared to an enhanced standard care intervention that provided computer-based, non-tailored information and advice regarding the use of contraceptive methods. The two primary outcomes of this trial include: 1) a behavioral outcome: the reported use of dual methods of contraception; and 2) a biological outcome: an incident or recurrent STI or unintended pregnancy. The hypotheses of this trial were: 1) the individualized intervention will result in a greater increase in dual contraceptive use than the standard care approach; and 2) the individualized intervention would result in greater protection against incident or recurrent cases of sexually transmitted infections and unplanned pregnancies.

NCT ID: NCT00413062 Completed - Contraception Clinical Trials

Efficacy and Safety Study of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing DRSP/EE (292002)(P05722)

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess contraceptive efficacy, vaginal bleeding patterns (cycle control), general safety and acceptability of the nomegestrol acetate-estradiol (NOMAC-E2) combined oral contraceptive (COC) in a large group of women aged 18-50 years.

NCT ID: NCT00403793 Completed - Contraception Clinical Trials

Hormonal Contraception in Healthy Young Men (P42306)(COMPLETED)(P06057)

Start date: October 2003
Phase: Phase 2
Study type: Interventional

Male volunteers receive a new hormonal contraceptive consisting of an implant releasing a hormone and hormone injections in order to investigate the suppressive effect on sperm production and reversibility of sperm production after end of treatment.

NCT ID: NCT00399165 Completed - Contraception Clinical Trials

Oral Androgens in Man-4: (Short Title: Oral T-4)

Start date: November 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration. In addition, we will compare the gonadotropin suppression mediated by a dose of testosterone enanthate (400 mg twice daily) that would be expected to maintain the serum testosterone in the normal range throughout the day, with the same dose (800 mg once daily) administered once daily. This larger once-daily dose is expected to result in a higher peak and lower trough by the end of the dosing interval

NCT ID: NCT00397670 Completed - Contraception Clinical Trials

Open Label Study of the Safety and Contraceptive Efficacy of BufferGel® With Diaphragm

Start date: January 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to study the safety and contraceptive effectiveness of BufferGel used with a contraceptive diaphragm.

NCT ID: NCT00393198 Completed - Contraception Clinical Trials

Bleeding Pattern and User Satisfaction During Second Consecutive MIRENA® in Contraception and Treatment of Menorrhagia

Start date: October 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the bleeding pattern during the last 3 months of the first MIRENA® and the first year of the second MIRENA® use.