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Contraception clinical trials

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NCT ID: NCT01839643 Completed - Contraception Clinical Trials

Assessment of a Vaginal Ring With Meloxicam on Ovarian Cycle in Fertile Women

Start date: January 15, 2013
Phase: Phase 1
Study type: Interventional

In this study, the investigators propose to assess if a non-hormonal agent is absorbed by a local route (vaginal) and to observe the effect on follicular development.

NCT ID: NCT01823861 Completed - Contraception Clinical Trials

Mobile Technology for Improved Family Planning

MOTIF
Start date: May 2013
Phase: N/A
Study type: Interventional

An individual randomised controlled trial (RCT) to evaluate the effectiveness of a voice-based mobile phone health (mHealth) intervention to support post-abortion family planning (PAFP) at four Marie Stopes International clinics in Cambodia. The study seeks to address the research question: does a PAFP mHealth intervention increase use of contraception in Cambodia? STUDY RESULTS: http://www.who.int/bulletin/online_first/en/

NCT ID: NCT01816932 Completed - Contraception Clinical Trials

Home or Office Visit for the Insertion of Implantable Birth Control

Start date: June 2013
Phase: N/A
Study type: Interventional

This is a pilot study in which women who desire an etonogestrel implant will be randomized to either a home or office insertion visit. The purpose of this research is to study the interest in, feasibility of, and rates of insertion for implantable birth control (Implanon®/Nexplanon®) when inserted at home visit appointments compared to standard office visit appointments. The ultimate goal of the study is to reduce barriers to insertion of the etonogestrel implant and increase consistent and correct contraception use by introducing a previously unexplored method of access, the home visit.

NCT ID: NCT01811225 Completed - Contraception Clinical Trials

Smoking, Sex Hormones, and Pregnancy

Start date: December 2012
Phase: Phase 2
Study type: Interventional

The investigators aim to (1) examine the association between levels of progesterone (Prog), allopregnanolone (Allo), and the estradiol/progesterone (E2/P) ratios with smoking-related symptomatology during ad libitum smoking and (2) determine the association between Prog, Allo, and E2/P with the changes in smoking-related symptomatology and response to nicotine following overnight abstinence

NCT ID: NCT01807715 Completed - Contraception Clinical Trials

Understanding Women's Contraceptive Expectations at the Time of a First Trimester Surgical Abortion

Start date: December 2012
Phase:
Study type: Observational

The investigators will conduct a voluntary anonymous survey at four separate Sacramento area family planning clinics. The investigators will ask the staff at each facility to offer a survey to all women 18 and older presenting to the clinic to have a first trimester (<12 weeks gestation) surgical abortion. Gestational age will be based on what the woman believes is her gestational age at presentation, before any evaluation in the clinic. Women who cannot understand or read the survey will be excluded. The investigators hope to implement the survey at these clinics for 3-4 months reaching a minimum of 200 women (based on a target population of 600 women receiving surgical first trimester abortions at these two clinics over a 3-4 month period with a 95% confidence interval).

NCT ID: NCT01797809 Completed - Contraception Clinical Trials

Qlaira rPMS (Regulatory Post Marketing Surveillance) Study in Korea

Start date: May 11, 2013
Phase:
Study type: Observational

The objective of this PMS is to gain information about safety and efficacy in real practice as a regulatory commitment required by KFDA (Korea Food and drug administration)

NCT ID: NCT01796613 Completed - Contraception Clinical Trials

Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy

Ring-Plus
Start date: June 2013
Phase: Phase 2/Phase 3
Study type: Interventional

The study is a multidisciplinary research project and has two main aims: 1. To determine the safety of a contraceptive vaginal ring (CVR) in women, with an emphasis on its effect on the vaginal microenvironment after different durations of use: the vaginal microbiome, biofilm formation on epithelial cells and rings, inflammation and immune activation in the vagina 2. To investigate the feasibility, acceptability and adherence to vaginal ring use in Rwandan women, including attitudes towards a future multi-purpose vaginal ring for prevention of both pregnancy and sexually transmitted infections (STI).

NCT ID: NCT01789879 Completed - HIV Clinical Trials

A Pharmacokinetic Evaluation of Levonorgestrel Implant and Antiretroviral Therapy

Start date: March 4, 2014
Phase: Phase 2
Study type: Interventional

The use of hormone contraception poses a significant challenge for the estimated 16 million HIV-infected women of childbearing age. This is due to known drug interactions with antiretroviral therapy (medicines used to treat HIV) that may jeopardize contraception effectiveness. By evaluating the impact of antiretroviral therapy on a levonorgestrel subdermal implant, the most widely available hormone implant in low and middle-income countries, this study will translate its findings into an evidence-based approach to co-manage these important medications. The investigators hypothesize that women receiving nevirapine or efavirenz-based antiretroviral therapy will have a significant decrease in the mean levonorgestrel plasma concentration measured six months after the implant's insertion as compared to those women who are not taking antiretroviral therapy. Although the implant's efficacy may be retained initially, the investigators propose that a decrease in levonorgestrel concentrations in women receiving antiretroviral therapy may jeopardize the implant's effectiveness near the end of its intended duration of use (5 years).

NCT ID: NCT01746758 Recruiting - HIV Clinical Trials

Mobile Phone Text Messaging Referral

SMS4Health
Start date: August 2012
Phase: N/A
Study type: Interventional

The study hypothesis is that managed referral of patients at community level (from drug stores) increases uptake of reproductive health (RH) services at dispensary and health centre levels. The intervention is currently being implemented in 2 districts (Magu and Sengerema) in Mwanza Region on the northwest shore of Lake Victoria. It is nested within the IntHEC Community Randomised Trial which aims to evaluate the impact of a complex RH intervention on the uptake and integration of reproductive health services in 2 Regions in Tanzania (Mwanza and Iringa) and Niger (Say and Aguie) respectively. 18 wards per region were stratified according to geographical and economic criteria and randomly assigned to intervention or comparison wards. The SMS intervention is being implemented in 9 intervention wards in Mwanza Region only. 9 wards are followed for comparison.

NCT ID: NCT01740687 Completed - Contraception Clinical Trials

A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test

ESS-NSPAS
Start date: November 13, 2012
Phase:
Study type: Observational

The purpose of the post approval study is to evaluate the effectiveness and safety of the Essure System when a NovaSure Endometrial Ablation procedure is performed following a successful Essure Confirmation Test.