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Contraception clinical trials

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NCT ID: NCT06127199 Recruiting - Contraception Clinical Trials

Contraceptive Efficacy Study of Ovaprene

Start date: December 19, 2023
Phase: N/A
Study type: Interventional

This will be a multi-center, single arm, open-label study of Ovaprene, a non-hormonal intravaginal ring, to investigate the contraceptive effectiveness, safety and acceptability of Ovaprene.

NCT ID: NCT06125470 Active, not recruiting - Contraception Clinical Trials

SihatMand Khandaan Healthy Families for Pakistan

SMK
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The SMK project's primary goal is to improve the status of SRH of women and adolescents within those targeted areas which feature inadequate progress on existing SRH indicators. The focus remains on empowering increasingly marginalized and vulnerable populations to exercise their reproductive rights, free of coercion, discrimination and violence. This will be achieved through the implementation of evidence-based and socio-culturally sensitive FP/ SRH interventions within ten districts of Pakistan. The aim of this project is therefore to evaluate the impact of a package of community and facility-based interventions on improving the SRH/ FP of the targeted population. In order to achieves this, a quasi-experimental pre & post evaluation intervention study with a formative phase, baseline assessment, intervention phase and finally an end-line assessment, consisting of both qualitative & quantitative monitoring & evaluation tools will be applied at the household, community, healthcare facility and district levels in all project areas. Furthermore, descriptive statistics will be tabulated on key indicators and stratified on selected variables. Means for continuous variables and proportion for categorical variables will be calculated at a 95% confidence interval within this study

NCT ID: NCT06081842 Not yet recruiting - Contraception Clinical Trials

Strengthening Contraceptive Counseling Services: Research Protocol for a Multi-phase Complex Intervention in Pakistan and Nigeria

Start date: November 2023
Phase: N/A
Study type: Interventional

High-quality contraceptive counseling can strengthen global efforts to reduce the unmet need for and suboptimal use of modern contraceptives. This study aims to identify a package of contraceptive counseling interventions for Pakistan and Nigeria designed to strengthen existing contraceptive services and determine its effectiveness in increasing clients' level of decision-making autonomy and meeting their contraceptive needs.

NCT ID: NCT06067256 Recruiting - Contraception Clinical Trials

A Multicentre, Prospective, Open-label, Non-comparative Study

Start date: July 20, 2023
Phase: Phase 4
Study type: Interventional

As there are no recent studies conducted in Italy on the profile of this COC, the purpose of this study is to evaluate its efficacy and tolerability in a given subset of women residing in Italy that are in need of contraception. Evaluate the cycle control: breakthrough bleeding (bleeding and/or spotting between cyclically regular onset of menses) of monophasic oral contraceptive pill Effimia® (NGM250 + EE35) in a population of women residing in Italy.

NCT ID: NCT06048536 Completed - Contraception Clinical Trials

Dose-finding Study of MR-130A-01 Contraceptive Transdermal Patch

Start date: December 22, 2023
Phase: Phase 2
Study type: Interventional

A single-center, randomized, open-label, parallel-group, multi-arm, phase II clinical trial in healthy women aged 18 to 35 years who have a documented ovulatory cycle prior to randomization.

NCT ID: NCT06042556 Completed - Contraception Clinical Trials

IUD Self-Removal: Evaluating an Online Guide for Self-removal in Clinical and Non-clinical Settings

Start date: April 3, 2021
Phase: N/A
Study type: Interventional

Investigators previously developed a guide to help people with IUD self-removal. In this randomized study, the goal is to see if this guide makes it easier for IUD-users to remove their own IUDs. The main question the study aims to answer is: -Does use of the previously developed IUD self-removal guide increase rates of self removal? Participants will: - Complete a pre-study survey - Be randomized to self-removal with use of the guide or no additional resource - Self-select participation at home or in clinic - Attempt IUD self-removal either at home or in clinic - Complete a post-study survey. Investigators will compare rates of successful self-removal between those randomized to the guide to those randomized to no additional resource to see if increases success.

NCT ID: NCT06028555 Recruiting - Contraception Clinical Trials

International Active Surveillance Study: Native Estrogen Estetrol (E4) Safety Study

INAS-NEES
Start date: June 28, 2023
Phase:
Study type: Observational

Multinational, comparative, prospective, active surveillance study that follows two cohorts. The primary objective of the study is to characterize and compare the risks of E4/Drospirenone (DRSP) with levonorgestrel-containing combined oral contraceptives (EE/LNG) in a study population that is representative of the actual users of these preparations. The main clinical outcome of interest is venous thromboembolism (VTE), specifically deep venous thrombosis (DVT) and pulmonary embolism (PE). Secondary objectives include measuring the occurrence of unintended pregnancy, assessing the risk of arterial thromboembolism (ATE), describing the drug utilization pattern, describing the baseline risk profile for VTE and ATE, and investigating outcomes associated with foetal exposure to E4/DRSP.

NCT ID: NCT06019533 Recruiting - Contraception Clinical Trials

A Trial on Contraceptive Efficacy, Safety and Tolerability of LVDS (Levonorgestrel Vaginal Delivery System) During 13 Cycles

Start date: August 9, 2023
Phase: Phase 3
Study type: Interventional

Multicentre, single arm phase III trial to assess the pearl index of LVDS. The trial lasts 13 cycles.The assessments include (but are not limited to) recording demographic data, pregnancy tests, gynaecological examinations, laboratory tests and a quality of life questionnaire. Adolescents will undergo DXA scans to measure bone mineral density (at selected sites only). The women will be provided with an e-diary app for their smartphone, to record IP use and vaginal bleeding.

NCT ID: NCT06009783 Recruiting - Contraception Clinical Trials

Utility of ChatGPT in Pre-vasectomy Counselling in an Office-based Setting

Start date: August 30, 2023
Phase: N/A
Study type: Interventional

The investigators wish to perform a pilot study at the Manitoba Men's Health Clinic to assess if pre-vasectomy counseling with ChatGPT can safely streamline the consultation process by reducing visit times, while increasing patient satisfaction with the consultation process.

NCT ID: NCT05994599 Recruiting - Contraception Clinical Trials

Comparative Bioavailability Study of Ethinyl Estradiol/Etonogestrel Vaginal Ring

Start date: July 28, 2023
Phase: Phase 1
Study type: Interventional

Single Dose Crossover Comparative Bioavailability Study of Ethinyl Estradiol/Etonogestrel Vaginal Ring (Delivering 0.015 mg/0.12 mg Per Day) Worn for 21 Days in Healthy Female Subjects