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Contraception clinical trials

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NCT ID: NCT03725358 Withdrawn - Contraception Clinical Trials

A Cluster-RCT to Increase the Uptake of LARCs Among Adolescent Females and Young Women in Cameroon.

Start date: September 2021
Phase: N/A
Study type: Interventional

The study investigators propose to test various supply-side approaches to increase the numbers of both SARCs (short-acting reversible contraceptives, i.e. the pill and injectable) and especially LARCs (long-acting reversible contraceptives, i.e. the IUD and implant) administered by health facilities to reproductive-age females in Cameroon, particularly adolescents who may be unmarried and/or nulliparous. The study investigators will do this via interventions at primary health facilities, which include training of providers on family planning; the introduction of a tablet-based decision support tool for counseling women on family planning; and increased subsidies for LARCs within the performance-based financing (PBF) system. This approach is expected to benefit the population directly by decreasing maternal mortality and undesired pregnancies and indirectly by reducing side effects that arise due to current one-size-fits-all FP (family planning) counseling; improving the health of children due to improved birth spacing; and increasing human capital accumulation among children and young (often school-age) potential mothers.

NCT ID: NCT03708809 Not yet recruiting - Contraception Clinical Trials

Immediate Versus Delayed Initiation of Intrauterine System

JANESS
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Contraception for teenagers and young adults presents a huge challenge for the clinician as more than half of all unintended pregnancies occur as a result of inconsistent or discontinued use of contraceptives . Possible solution is promoting the use of long acting reversible contraception, (LARC) among them the intrauterine device (IUD). IUD provide safe, highly effective, long-term contraception. Immediate IUD insertion after the termination of pregnancy (TOP) is a very convenient way to provide contraception as it is an opportune moment to carry out this short, easy, and safe procedure. Janess is a T-shaped intrauterine delivery system that was introduced lately, which slowly releases a small amount (13.5 mg) of levonorgestrel after its installation inside the womb and provides contraception for up to three years. The aim of this study to compare insertion of 13.5 mg levonorgestrel-releasing intrauterine system after surgical abortion immediately versus delayed insertion (at menstruation)

NCT ID: NCT03700658 Completed - Contraception Clinical Trials

A Study to Evaluate Injection Pain and Local Tolerability Following Subcutaneous (SC) Administration of TV-46046

Start date: January 15, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the local tolerability associated with the SC administration of TV-46046, and inform next steps of the TV-46046 development program.

NCT ID: NCT03657602 Completed - Contraception Clinical Trials

Immediate Postpartum Insertion of Contraceptive Intrauterine Devices

Start date: December 15, 2019
Phase: Early Phase 1
Study type: Interventional

In this randomized trial, investigators intend to determine the expulsion and discontinuation rate of immediate postpartum intrauterine devices in the patient population of the University of Oklahoma Women's Healthcare Specialists Clinic (OUWHSC).

NCT ID: NCT03656289 Withdrawn - Contraception Clinical Trials

Antepartum Etonogestrel Contraceptive Implant Insertion at Term

Start date: January 1, 2019
Phase: Phase 1
Study type: Interventional

Short-interval pregnancy (SIP) or rapid, repeat pregnancy is defined as a pregnancy within one year of prior delivery. These pregnancies are often unintended and are associated with adverse risks. Low contraceptive initiation during the postpartum period is a contributing factor to SIP. This study will be the first to investigate the initiation of a highly-effective, immediately active contraceptive device during the antepartum period. The antepartum period serves as an ideal time for postpartum contraception counseling, due to patients' active involvement with the healthcare system. The pharmacokinetic analysis proposed in this study will be the first to investigate whether and to what extent ENG hormone crosses the placenta. This data will enrich understanding of the pharmacology of exogenous progestins administered during pregnancy and provide information that can be incorporated into future patient counseling regarding the risks of fetal exposure with exogenous progestin use.

NCT ID: NCT03598088 Completed - Contraception Clinical Trials

Safety and Acceptability Study of a Non-Hormonal Ring

Start date: May 23, 2018
Phase: N/A
Study type: Interventional

This is a feasibility, multi-center, open-label, non-significant risk device study for a non-hormonal contraceptive ring.

NCT ID: NCT03589040 Recruiting - HIV Clinical Trials

Darunavir and Rilpivirine Interactions With Etonogestrel Contraceptive Implant

DRIVE-1
Start date: September 25, 2018
Phase: Phase 2
Study type: Interventional

This study will evaluate the pharmacokinetic properties of rilpivirine and darunavir when used in combination with etonogestrel

NCT ID: NCT03589027 Recruiting - Contraception Clinical Trials

Darunavir and Rilpivirine Interactions With Levonorgestrel Implant

DRIVE-2
Start date: August 7, 2018
Phase: Phase 2
Study type: Interventional

This study will evaluate the pharmacokinetic properties of Rilpivirine and Darunavir when used in combination with Levonorgestrel

NCT ID: NCT03585712 Completed - Contraception Clinical Trials

Effect of Norgestrel 75 mcg on Cervical Mucus and Ovarian Activity During Perfect Use, After One Delayed Intake and After a Missed Pill

Start date: July 24, 2018
Phase: Phase 2
Study type: Interventional

Norgestrel 75 mcg is a progestin-only pill (POP), which is a kind of oral birth control pill. To be effective in preventing pregnancy, this kind of birth control pill is supposed to be taken every day at the same time, without delaying the intake for more than 3 hours. This study aims to find out if taking the pill 6 hours late or not taking it for one day will affect the way it works.

NCT ID: NCT03585361 Completed - Pregnancy Clinical Trials

Utilizing All Health System Contacts to Offer Postpartum Family Planning (PPFP) in Ethiopia

Start date: February 20, 2017
Phase: N/A
Study type: Interventional

This study is investigating whether use of postpartum family planning (PPFP) increases if messages on PPFP and, if desired, PPFP services are integrated into as many contacts as possible between women/couples and the health system during pregnancy and the first year after birth. Health system contacts may be at health facilities (including antenatal, labor and delivery, postnatal, and child immunization visits) or, with Ethiopia's Health Extension Program, at households or health posts in the community.