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Constipation clinical trials

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NCT ID: NCT04588766 Recruiting - Cerebral Palsy Clinical Trials

Chronic Constipation With Cerebral Palsy

Start date: October 15, 2020
Phase:
Study type: Observational

This study was performed to evaluate posture, sleep, physical activity and quality of life in individuals with chronic constipation Cerebral Palsy.

NCT ID: NCT04587635 Completed - Clinical trials for Constipation - Functional

Evaluation of Changes in Bowel Movement Frequency Following the Consumption of PHGG in Adults With Constipation

TYPHOON
Start date: September 16, 2020
Phase: N/A
Study type: Interventional

Evaluation of Changes in Bowel Movement Frequency Following the Consumption of Partially Hydrolyzed Guar Gum (PHGG) in Adults with Constipation

NCT ID: NCT04570072 Not yet recruiting - Clinical trials for Comorbidity of Depression and Constipation

Effect of Probiotic on Comorbidity of Depression and Constipation

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Depressive disorder, also known as depression, is a type of mood disorder characterized by persistent low mood. The incidence of depression worldwide is about 6%. The high comorbidity rate between depression and constipation indicated the role of the gut-brain axis in depression. Growing evidence suggested that the gut microbiota plays a key role in the development of depression. Probiotics can effectively improve constipation and regulate gut microbiota, and showed potential in alleviating depression. This study investigated the effect of formula probiotic (containing Lactobacillus paracasei, Bifidobacterium animals, Bifidobacterium longum, Bifidobacterium bifidum, and Lactobacillus plantarum) on the comorbidity of depression and constipation.

NCT ID: NCT04569656 Completed - Parkinson Disease Clinical Trials

Treatment of Chronic Constipation in Parkinson's Disease

PHGG-PD
Start date: February 2, 2016
Phase: Phase 2
Study type: Interventional

Chronic constipation is the most common gastrointestinal symptom reported by PD patients; it could be one of the manifestations of disease onset. PHGG fiber is extracted from a herbaceous plant (Cyamopsis Tetra-Gonolobus, family: Leguminosae) of Indian origin: it produces 5/9 pods containing seeds which produce the famous guar gum, that is a natural polysaccharide.

NCT ID: NCT04547816 Recruiting - Clinical trials for Functional Constipation

Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse

Start date: July 1, 2020
Phase: Phase 3
Study type: Interventional

This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse

NCT ID: NCT04534465 Completed - Constipation Clinical Trials

Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.

Start date: February 13, 2013
Phase: Phase 4
Study type: Interventional

Study to gather information on the acceptability of a new flavor system with increasing levels of 2, 4, 6 g or higher of the sugar alcohol Mannitol for Polyethylene glycol (PEG) 3350 a drug stimulating bowel movement to pass stool in subjects having infrequent bowel movements. The taste of the various preparations will be measured by use of a rating scale.

NCT ID: NCT04534036 Completed - Constipation Clinical Trials

Tolerability and Functional Assessment of a Novel Children's Synbiotic

PDS-08™
Start date: August 13, 2020
Phase: N/A
Study type: Interventional

Recent data support the use of specific probiotic strains in a pediatric population. However, given the wide number of commercial products available, and contradictory data in the literature, healthcare providers and consumers are uncertain about whether or not to use probiotics in children and which one(s) to choose. While much progress has been made in understanding the gastrointestinal microbiota and its role in the balanced development of the infant immune system, the tolerability and efficacy of introducing beneficial microbes into the pediatric gastrointestinal tract remain underexplored. The purpose of this study is to investigate the effect of a 9 strain synbiotic consortium comprised of strains with previous pediatric clinical data for use in modulating airway sensitivity, gastrointestinal discomfort, dermatological inflammation, and reduction in the duration and severity of upper respiratory tract infections in a pediatric population.

NCT ID: NCT04532879 Withdrawn - Clinical trials for Rome IV Functional Constipation

HygiRelief Procedure and HygiSample Evaluation for Functional Constipation

Start date: September 2021
Phase: N/A
Study type: Interventional

This study has a single center, prospective, open label design. The population will include patients diagnosed with Rome IV Functional Constipation who are at the time of study enrollment being managed with a stable dose of Linzess. They will stop taking their Linzess, undergo monitoring of bowel habits for 2 weeks, have a HygiRelief procedure and then undergo an additional 2 weeks of bowel habit monitoring.

NCT ID: NCT04527640 Not yet recruiting - Constipation Clinical Trials

Effects of Synbiotics Supplementation on the Uremic Toxin Indoxyl Sulfate Level and Constipation in End-stage Renal Disease Patients Undergoing Hemodialysis

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

This is a double-blind, placebo-controlled, randomized clinical trial conducted to evaluate the effects of synbiotics supplementation on the level of the uremic toxin indoxyl sulfate, symptoms of constipation, and constipation-related quality of life in end-stage renal disease patients undergoing hemodialysis.

NCT ID: NCT04525248 Not yet recruiting - Constipation Clinical Trials

Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum