Clinical Trials Logo
  1. Home
  2. Conjunctivitis, Bacterial
  3. NCT01721694

Antibiotic Steroid Combination Compared With Individual Administration in the in the Treatment of Ocular Inflammation and Infection

Keratitis Clinical Trial

Official title:
Association of Azithromycin 1,5%/Loteprednol 0,5% Eye Drops Versus Individual Administration of Azithromycin 1,5% and Loteprednol 0,5% in the Treatment of Ocular Inflammation and Infection

Clinical Trial Summary

To evaluate the efficacy and safety of fixed combination of azithromycin 1.5% + 0.5% Loteprednol eye drops for the treatment of ocular inflammation and infection associated bacterial blepharitis and / or keratitis and / or conjunctivitis compared with the individual administration of azithromycin 1.5% and 0.5% Loteprednol (separately).

Clinical Trial Description

Estimated to be admitted a total of approximately 60 patients showing blepharitis and / or keratitis and / or conjunctivitis: 30 patients will be assigned to the group of Azithromycin 1.5%/Loteprednol 0.5% Eye Drops (fixed combination) + placebo and 30 patients will be assigned to the group of Azithromycin 1.5% + 0.5% Loteprednol (separately) ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01721694
Study type Interventional
Source Adapt Produtos Oftalmológicos Ltda.
Contact
Status Withdrawn
Phase Phase 3
Start date December 2012
Completion date May 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT00513734 - A Comparison of Hydrogel Dressings and Ocular Lubricants in the Prevention on Corneal Damage in the Critically Ill N/A
Enrolling by invitation NCT03436576 - Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye Phase 3
Recruiting NCT06229379 - The Effects of a Large Language Model on Clinical Questioning Skills N/A
Completed NCT01268306 - Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses Phase 4
Completed NCT01028027 - Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis Phase 3
Recruiting NCT05432336 - Complex Ocular Infection, Optimization of Microbiological Diagnosis
Completed NCT04169061 - Impact of Acthar on Everyday Life of Participants With Severe Keratitis Phase 4
Completed NCT03237936 - Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis Phase 4
Completed NCT00001734 - Screening for NEI Clinical Studies N/A
Recruiting NCT05255107 - Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers Phase 2/Phase 3
Recruiting NCT05255016 - Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers Phase 2/Phase 3
Terminated NCT05250583 - Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Treatment-Resistant Keratitis Phase 2
Recruiting NCT02865876 - Effectiveness of Corneal Accelerated Crosslinking for Infectious Keratitis Phase 3
Terminated NCT02116062 - Robotic Surgery of the Ocular Surface N/A
Recruiting NCT00838422 - Reliability of Pachymetry Measurement With FD-oCT, ORA, Confoscan 4 and Ultrasound N/A
Completed NCT00949468 - Microbiological Keratitis in a Countryside City of Brazil N/A
Completed NCT03586505 - Tolerance to Light for Patients Suffering From Keratitis N/A
Recruiting NCT04420962 - Automated Quantitative Ulcer Analysis Study
Completed NCT02186431 - Contact Lenses and Infiltrative Keratitis N/A
Completed NCT05538793 - Deep Learning for the Discrimination Among Different Types of Keratits: a Nationwide Study