Congestive Heart Failure: Causes of Sudden Worsening

Status Recruiting

Clinical Trial Summary

The purpose of the study is to recognize main causes of acute decompensation of chronic congestive heart failure.

Clinical Trial Description

Congestive heart failure (CHF) presents a very significant cause of morbidity and mortality. The prevalence of CHF is between 2 and 4% and rises with age (in 70- to 80-year-old people is between 10 and 20%). CHF is the cause of 5% of all acute hospital admissions and accounts for 2% of expenses on health. The most common causes of worsening of the chronic CHF are ischemia, arrhythmias, valvular dysfunction, systemic or pulmonary hypertension, volume overload or fluid retention, high output conditions (infection, anemia, thyrotoxicosis), drugs (NSAIDs, cyclo-oxygenase (COX) inhibitors, thiazolidinediones) and medication nonadherence. The goal of this study is to determine the proportion of various reasons of acute worsening of CHF, using commonly available methods including assessment of serum drug levels. ;

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01081925
Study type	Observational
Source	University Hospital Hradec Kralove
Contact	Radek Pelouch, MD
Phone	00420495834740
Email	pelouch@centrum.cz
Status	Recruiting
Phase	N/A
Start date	February 2010
Completion date	February 2012

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