Metabolic Derangements in Acute Heart Failure Syndrome

Congestive Heart Failure Clinical Trial

Official title:

Metabolic Derangements in Acute Heart Failure Syndrome

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00682175
• Other study ID #: 08-169
• Status: Terminated
• Phase: N/A
• First received: May 20, 2008
• Last updated: March 25, 2009
• Start date: May 2008
• Est. completion date: March 2009

Study information

• Verified date: March 2009
• Source: The Cleveland Clinic
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

To determine the association of both neurohormonal and hemodynamic alterations associated with metabolic abnormalities in acute heart failure syndrome.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 100
• Est. completion date: March 2009
• Est. primary completion date: March 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult (age > 18 yrs) patients admitted to the Heart Failure Intensive Care Unit (H22) with Acute Heart Failure Syndrome (AHFS) requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.

Exclusion Criteria:

• History of Congenital Heart Disease.

• Acute HF in the setting of acute myocardial infarction.

• Severe Anemia

• Patients listed for cardiac transplantation.

• Terminal Malignancy, AIDS or CNS disease.

• Concomitant sepsis, ARDS, trauma, aortic dissection, or pericardial tamponade

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Congestive Heart Failure
• Heart Failure
• Metabolic Diseases

Intervention

Other:
• Observational
Pulmonary Artery pressure (PA), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), and cardiac index (CI). This data will be collected after 24 ± 2 and 48 ± 2 hours of standard heart failure therapy

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The Cleveland Clinic