Clinical Trials Logo

Clinical Trial Summary

To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural association, and to assess the diagnostic abilities of structure parameters.


Clinical Trial Description

A cross-sectional study. A total of 129 congenital cataract patients after congenital cataract extraction (40 in GFCS and 89 in NGFCS) were enrolled in this study from December 2020 to March 2021. All participants, age range from 4 to 18 years old, completed OCT examinations (including macular structure parameters, optic nerve fiber layer thickness periphery retinal nerve fiber layer [pRNFL], and sub foveal choroidal thickness [SFCT]). All the NGFCS participants underwent OCTA examinations (including vessel density (VD) and perfusion density (PD) of macular and peripapillary area.). Linear regression models were used to examine the effect of various factors on different ocular parameters. Vascular-structural associations were assessed with Spearman correlation. Diagnostic ability was evaluated with area under the receiver operating curve (AUC). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05446077
Study type Observational [Patient Registry]
Source Sun Yat-sen University
Contact
Status Completed
Phase
Start date December 1, 2020
Completion date March 1, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT05136209 - Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy N/A
Recruiting NCT05275764 - Comparison of the Efficacy of Intraocular Lens Optic Capture and In-the-bag Implantation Over 1 Year in Children With Congenital Cataract
Recruiting NCT03342794 - Morphologic and Biometric Characteristics of Preexisting Posterior Capsule Defects in Congenital Cataracts During the First Year of Life N/A
Completed NCT01297153 - Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery Phase 4
Completed NCT04120818 - Inflammatory Cytokines in Congenital Cataract After Lensectomy and Anterior Vitrectomy
Recruiting NCT04824963 - Analysis of Related Factors Affecting the Secondary Implantation of Intraocular Lens in Congenital Cataract
Recruiting NCT04323982 - Comparison of Traditional Cataract Surgery and Traditional Surgery Combined Triamcinolone Staining N/A
Completed NCT02158325 - Capsulorhexis Size and Capsular Outcome N/A
Completed NCT03621579 - Analysis of Retinal Nerve Fiber Layer and Macular Thickness After Congenital Cataract Surgery N/A
Recruiting NCT03564990 - The Impact of Interactive, Multifaceted Approach Education on Congenital Cataract N/A
Not yet recruiting NCT05282147 - Digital Imaging Versus Ophthalmoscopy N/A
Not yet recruiting NCT03125785 - The Effect of Ophthalmic Solutions on Contact Lenses Used After Surgery for Congenital Cataract Investigated in Vivo N/A
Recruiting NCT04976608 - Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery
Completed NCT03778086 - Iridocorneal Angle and Anterior Segment Structure in Eyes of Children With Cataract
Recruiting NCT03230799 - Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery N/A
Recruiting NCT04759560 - Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction
Completed NCT02132312 - A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement Phase 3
Completed NCT01136473 - Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients N/A
Completed NCT03242629 - Comparison Between Oral and Enema of Chloral Hydrate N/A
Completed NCT04077489 - Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract N/A