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Concussion, Intermediate clinical trials

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NCT ID: NCT06260072 Recruiting - Clinical trials for Concussion, Intermediate

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Start date: February 10, 2020
Phase: Phase 2
Study type: Interventional

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

NCT ID: NCT05943561 Not yet recruiting - Concussion, Mild Clinical Trials

Biomarkers in Concussion

Start date: September 2023
Phase:
Study type: Observational

This will be an observational study measuring serum Neurofilament Light Chain concentrations and associated symptoms, with a control branch, and a post-concussion branch.

NCT ID: NCT05741411 Recruiting - Clinical trials for Mild Traumatic Brain Injury

Facilitating Access to Specialty Treatment

Start date: March 11, 2024
Phase: N/A
Study type: Interventional

The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel mobile health intervention, designed to reduce disparities in access to specialty care through the use of remote patient monitoring (RPM) to facilitate care hand-off from the emergency department (ED) to concussion specialty care. Participants will report their symptoms and activity once daily through RPM chat technology that is linked to their electronic health record and prompts referral to specialty care.

NCT ID: NCT05636020 Recruiting - Clinical trials for Traumatic Brain Injury

Intervention to Change Affect Recognition and Empathy

ICARE
Start date: March 15, 2023
Phase: N/A
Study type: Interventional

Determine the feasibility, practicality, and early efficacy of a TeleRehab program (ICARE) to improve outcomes for persons with traumatic brain injury (TBI) in recognizing and responding to others' emotions alongside their care partner (CP).

NCT ID: NCT05623046 Recruiting - Concussion, Brain Clinical Trials

Building Emotional Self-Awareness Teletherapy (BEST)

BEST
Start date: February 23, 2023
Phase: N/A
Study type: Interventional

To examine the feasibility, acceptability, and preliminary efficacy of a remotely delivered intervention for civilians and service members with mild traumatic brain injury (mTBI) who have difficulty recognizing and regulating their emotions. Post-treatment outcomes of interest include emotional self-awareness and regulation, resiliency, and affective symptoms.

NCT ID: NCT04248218 Completed - Pediatric ALL Clinical Trials

Concussion Active Rehabilitation

Start date: August 12, 2019
Phase: N/A
Study type: Interventional

In this study, the investigator plans a randomized trial of active rehabilitation and standard care for acute concussion management. The investigator hypothesizes that patients with acute concussions managed with active rehabilitation will have decreased risk of prolonged concussion symptoms.

NCT ID: NCT04074486 Completed - Brain Injuries Clinical Trials

Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC

BSC-CI-NPC
Start date: October 2, 2019
Phase:
Study type: Observational

This study is designed to collect data which will be used to associate changes in EEG, neurocognitive performance, eNPC and clinical symptoms in concussion subtypes. The study will recruit males and females, 13-50 years old, from Concussion Centers/Programs, Sports Venues and Emergency Departments (ED) across the country, over an 18-month period (Phase 2, 12 months for Algorithm Development and Norming, and Phase 3, 6 months for Validation).

NCT ID: NCT03963804 Completed - Clinical trials for Brain Injuries, Traumatic

Objective Brain Function Assessment of mTBI/Concussion

CAS13-25
Start date: June 11, 2018
Phase:
Study type: Observational

This study (Part 3) is designed to build a database including EEG, neurocognitive performance, clinical symptoms, history and other relevant data, which will be used to derive a multimodal EEG based algorithm for the identification of concussion and tracking of recovery.

NCT ID: NCT03671083 Completed - Clinical trials for Brain Injuries, Traumatic

Validation of Brain Function Assessment Algorithm for mTBI/Concussion

CAS13-25V
Start date: October 1, 2018
Phase:
Study type: Observational

This study is Part 2 of data collection from 13-25 years old subject population for validation of previously derived algorithms. This data will be combined with that collected under NCT02957461 (Part 1 with subject age range 18-25 years) for the final analyses of validation of the algorithms.

NCT ID: NCT03624634 Completed - Concussion, Mild Clinical Trials

Assessment of the Effects of Concussion on Adolescent Rugby Union Players

Start date: August 1, 2016
Phase:
Study type: Observational

200 adolescent rugby players (aged 15-19) from the Senior Cup Teams of 5 Rugby Playing schools (Members of Irish Schools Rugby) will be invited to enroll for inclusion in the study. The study will collect data on brain health, including computer based skill testing, eye tracking and balance and on task completion, cover existing tests in the established SCAT 3 alongside response to exercise testing and a clinical examination including baseline blood tests known to influence recovery from concussion in a rugby playing population of adolescent schoolboys. The initial data will be taken before the 2016/2017 season starts. The volume of rugby training and match play will be recorded along with activity monitoring in general. For those subjects who sustain concussion a dedicated clinic will provide all after care including repeat clinical examination and magnetic resonance imaging along with a graduated return to exercise and a compressive rehabilitation programme at Sports Surgery Clinic (SSC). A Consultant Sports Physician will manage the return to play programme with an exercise, cognitive, balance, eye movement and neck strength programme.