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Concussion, Brain clinical trials

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NCT ID: NCT05886400 Recruiting - Clinical trials for Mild Traumatic Brain Injury

The Effects of Environmental Distractions on SCAT6 Outcomes

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of visual and auditory distractions on SCAT5 scores. The study is designed to identify the effects of about 80 participants completing the SCAT5 in college-aged athletes. All participants will perform the same tasks in two settings (distracted and non-distracted). The central hypothesis is that there will be a significant association between distractions and a lower score on the SCAT5. The cognitive screening, neurological screen, and mBESS should showcase a decrease scores during the distracted environment.

NCT ID: NCT05825027 Enrolling by invitation - Clinical trials for Mild Traumatic Brain Injury

Risk Stratification in Children With Concussion

RSiCC
Start date: May 23, 2023
Phase:
Study type: Observational

This project will measure concussion symptoms, biological markers, and academic and social factors across the first year postconcussion to develop a model that enables early identification of and symptom management for children at higher risk for persistent postconcussive symptoms. Findings will provide novel insights into the longer-term effects of concussion on children's physical, psychological, and social well-being and support the development of personalized healthcare and school-based plans to reduce disparities in children's ability to return-to-learn and -play and improve postconcussion quality of life.

NCT ID: NCT05819489 Recruiting - Concussion, Brain Clinical Trials

A Comparison of Dynamic Vision & Balance Between College Athletes & Controls

Start date: August 31, 2021
Phase:
Study type: Observational

The purpose of this study is to determine the value of including dynamic vision testing into California State University, Northridge (CSUN) Athletics' established concussion protocol. The study's hypotheses are 1) dynamic vision testing will reveal vision impairments right after a person sustains a concussion, 2) these impairments may still be present upon clearance to return to play.

NCT ID: NCT05736692 Withdrawn - Sleep Disorder Clinical Trials

Addressing Sleep in Adolescents Post-Concussion ("ASAP Study")

ASAP
Start date: January 30, 2024
Phase: N/A
Study type: Interventional

Hundreds of thousands of adolescents experience protracted recoveries from concussion, which can affect all aspects of their lives and create family and societal burden. Research suggests that interventions to improve their sleep quantity and/or quality could improve recovery from concussion, but current treatment models are costly and onerous for families, fit poorly with integrated care models, and leave youth and their families to suffer months of protracted burden. This study will evaluate the efficacy of a promising brief behavioral sleep intervention, which could prove to be a powerful new tool to head off protracted symptom burden.

NCT ID: NCT05719844 Recruiting - Concussion, Brain Clinical Trials

Interest of an Attentional Evaluation by a Computerized Battery in the Management of Concussion in Young Rugby Players

NeuropsyCor
Start date: March 9, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to test the ability of a computerized neuropsychological battery to identify attentional disorders resulting from a concussion occurring during the practice of rugby. Thirty young people with a concussion (11-25 years old) will take several neuropsychological tests. Researchers will compare their results with those of young athletes without concussion to see the effect of concussion.

NCT ID: NCT05685121 Recruiting - Concussion, Brain Clinical Trials

A Wrist-Worn Nerve Stimulator for Remediating Persistent Post-Concussive Symptoms in Adolescents

Start date: October 22, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to test a wearable nerve stimulator in adolescents with persistent post-concussive symptoms. The main questions it aims to answer is whether the device will reduce clinical symptom burden, reduce cognitive deficits, and aid in the recovery of clinical symptoms. Participants will wear the device daily for six weeks and complete a series of assessments.

NCT ID: NCT05682677 Recruiting - Depression Clinical Trials

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

Start date: September 19, 2023
Phase: N/A
Study type: Interventional

The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive PACT plus 20 sessions of iTBS or sham iTBS over 4 weeks. Assessments will occur at baseline, 2 weeks, 4 weeks, and 8 weeks. Researchers will compare the PACT+iTBS group to the PACT+sham iTBS group to see if PACT+iTBS is associated with more depression improvement.

NCT ID: NCT05663034 Recruiting - Depression Clinical Trials

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Start date: May 10, 2024
Phase: N/A
Study type: Interventional

This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and mindfulness-based treatment for insomnia (MBTI) in treating insomnia symptoms and ameliorating depressive symptoms in persons with mild to moderate TBI and comorbid Post-Traumatic Stress Symptoms (PTSS) and insomnia symptoms in a 360 patients. Participants will undergo assessment (psychosocial questionnaires, neurocognitive testing, sleep monitoring) at baseline, at the end of treatment, and at 6- and 12-weeks post-treatment. The primary outcome is sleep as measured by the Insomnia Severity Index (ISI).

NCT ID: NCT05623046 Recruiting - Concussion, Brain Clinical Trials

Building Emotional Self-Awareness Teletherapy (BEST)

BEST
Start date: February 23, 2023
Phase: N/A
Study type: Interventional

To examine the feasibility, acceptability, and preliminary efficacy of a remotely delivered intervention for civilians and service members with mild traumatic brain injury (mTBI) who have difficulty recognizing and regulating their emotions. Post-treatment outcomes of interest include emotional self-awareness and regulation, resiliency, and affective symptoms.

NCT ID: NCT05562232 Not yet recruiting - Clinical trials for Mild Traumatic Brain Injury

The Effect of Creatine Monohydrate on Persistent Post-concussive Symptoms

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study, is to investigate whether creatine monohydrate as a supplement reduces the number and severity of symptoms in patients with persistent post-concussive symptoms through self-reported post-concussion symptoms questionnaires.