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Concussion, Brain clinical trials

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NCT ID: NCT05736692 Withdrawn - Sleep Disorder Clinical Trials

Addressing Sleep in Adolescents Post-Concussion ("ASAP Study")

ASAP
Start date: January 30, 2024
Phase: N/A
Study type: Interventional

Hundreds of thousands of adolescents experience protracted recoveries from concussion, which can affect all aspects of their lives and create family and societal burden. Research suggests that interventions to improve their sleep quantity and/or quality could improve recovery from concussion, but current treatment models are costly and onerous for families, fit poorly with integrated care models, and leave youth and their families to suffer months of protracted burden. This study will evaluate the efficacy of a promising brief behavioral sleep intervention, which could prove to be a powerful new tool to head off protracted symptom burden.

NCT ID: NCT05062148 Withdrawn - Clinical trials for Traumatic Brain Injury

Fundamental and Applied Concussion Recovery Modality Research and Development: Applications for the Enhanced Recovery

Start date: September 2021
Phase: N/A
Study type: Interventional

This research is being done to understand the role of different recovery methods in healing time after athletic or sports related concussion.

NCT ID: NCT03575741 Withdrawn - Concussion, Brain Clinical Trials

Postural Control in Children and Adolescents After Suffering From a Concussion

Start date: October 8, 2018
Phase:
Study type: Observational [Patient Registry]

Sport-related concussions occur during different types of sport and are still an underestimated brain injury. Especially children are affected due to their lacking movement control and thereby at higher risk of situations leading to concussion. However, research about the rehabilitation of balance and coordination in children after sustaining a concussion is lacking. Therefore, the return-to-sport question cannot be answered reliable due to the missing understanding of the underlying mechanisms disturbing coordination, yet. Analyzing postural control, meaning the ability of the body controlled by the brain to maintain balanced, is suggested to be a valid method to investigate movement coordination. A newer method to analyze postural control using reflective marker data will be used to study the rehabilitation process. The findings may help to improve concussion treatment and give implication to the return-to-sport decision. The investigators expect to see an altered postural control after sustaining a concussion visible in the movement amplitude especially short after the injury. Moreover, the researchers assume coordination patterns which are not visible to be altered for an extended time period of up to 30 days as well. Participants will be children aged 10 to 16 years and the aim is to recruit 30 children and adolescents who suffer from a concussion. The data of the concussed participants will be compared with data of healthy volunteers.

NCT ID: NCT03249675 Withdrawn - Concussion, Brain Clinical Trials

Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment, Young Adults and Adults

Start date: July 5, 2017
Phase:
Study type: Observational

Concussion is widely recognized as a major public health concern in the United States and worldwide. Although many concussions resolve completely and spontaneously, almost 1 in 4 patients will go on to experience post-concussion syndrome (PCS). In the United States, PCS diagnoses have increased 100% from 2010-2015. Concurrently, recent advances in EEG evoked response potential analysis have led to a novel technique for assessing brain network activation (BNA) patterns. The purpose of this study is to explore the use of BNA in individuals who are diagnosed with PCS or have the risk of experiencing PCS due to a recent injury.

NCT ID: NCT02959294 Withdrawn - Concussion, Brain Clinical Trials

Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries

C-TBI
Start date: November 30, 2018
Phase: Early Phase 1
Study type: Interventional

Concussion is the most common type of brain injury throughout life. Study is seeking improvement of long-term residua following adolescent and adult post-traumatic injuries often associated with contact sports and accidental causes. Typically defined as reversible head injury with temporary loss of brain function. Symptoms range from physical, cognitive, pain (headache) and emotional signs consistent with TBI and Post-Traumatic Stress Syndrome. Use of AD-cSVF parenteral delivery to encourage repair of damage and decreased function following concussion, particularly in contact, repetitive sports injuries. Range of damage is measured in Grade I-III according to graduated severity. Unfortunately, less information is available about repetitive concussions and the long-term health issues.