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Clinical Trial Summary

This study aims to examine the inflammatory response mediated by MMP-8 (Matrix metalloproteinase-8 ) level in peri-implant sulcus fluid adjacent to screw-retained, cemented or using the Acuris-system fixed single implant crowns as well as changing of the marginal bone level within the first year after implant restoration. Furthermore periodontal parameters, patient satisfaction and possible occurring biological or technical complications will be evaluated.


Clinical Trial Description

After giving their written consent volunteers will be screened and eligible subjects will be randomized to three different groups. In group 1 Acuris® is used as fixation type; in group 2 screw retention, and in group 3 cementation is used. After 3 months of submerged healing the dental implants will be restored with all ceramic single implant crowns, fixed by using the randomized fixation mode. Follow-up visits till one year after implant restoration will be performed. At least 11 study visits during 16 months will be conducted. ;


Study Design


Related Conditions & MeSH terms

  • Complications: Inflammatory Reactions, Mechanical Complications
  • Inflammation

NCT number NCT04707716
Study type Interventional
Source Medical University of Graz
Contact Elisabeth Steyer, Dr.
Phone 0043 69911221489
Email elisabeth.amberger@medunigraz.at
Status Recruiting
Phase N/A
Start date March 4, 2021
Completion date November 2024