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Complication clinical trials

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NCT ID: NCT03708874 Completed - Shoulder Pain Clinical Trials

Pain Management of Emergency Laparoscopic Cholecystectomy in Patients With Acute Cholecystitis

Start date: October 9, 2018
Phase:
Study type: Observational [Patient Registry]

Patients diagnosed with acute cholecystitis benefit from emergency laparoscopic cholecystectomy (LC). Patients who had emergency LC showed improvement in quality of life in one month compared to those treated. Delayed LC (after the acute cholecystitis has passed) and less time to recover from work. This strategy reduces the risk of repeated referrals with more pain or pancreatitis. There are many studies on the efficacy of intraoperative intraperitoneal bupivacaine(IPBV) with elective LC on pain of IPBV. However, the prospective study of reducing the postoperative pain of emergency LC - IPBV is very few. This study will be conducted to evaluate the efficacy of IPBV in patients with emergency LC.

NCT ID: NCT03608267 Completed - Bariatric Surgery Clinical Trials

Safety and Feasibility of Endomina, an Candy Cane Syndrome Endoluminal Suturing Device

Endomina
Start date: March 6, 2018
Phase: N/A
Study type: Interventional

Surgery is currently the only effective treatment for morbid obesity and can be divided into restrictive surgeries (Lap Band and Sleeve gastrectomy), malabsorptive surgeries (Biliary pancreatic deviation and duodenal switch) or a combination of both (RYGBP). This latter technique is the most common and most effective surgical procedure performed worldwide and has been processed to be an effective treatment of morbid obesity and its complications, achieving excess weight loss of 65 to 80 %; 1-2 years after surgery (1,2). Morbidity after RYGB includes the candy cane syndrome or afferent loop syndrome. Candy cane Roux syndrome in patients who have undergone RYGB refers to an excessively long blind afferent Roux limb at the gastrojejunostomy causing postprandial pain often relieved by vomiting. It is believed that the blind afferent limb ("candy cane") acts as an obstructed loop when filled with food (often preferentially), and the distention of the loop causes pain until the food either spills into the Roux limb or is vomited back out (3). Patients have been reported presenting as early as three months and as late as 11 years after their initial RYGB, typically with symptoms of postprandial epigastric pain, nausea, vomiting, and reflux or food regurgitation (4). The diagnosis is confirmed by upper gastrointestinal contrast studies or endoscopy. On upper gastrointestinal series, the afferent limb fills before contrast spills into the Roux limb. On upper endoscopy, the afferent limb is usually the most direct outlet of the gastrojejunostomy (3). The treatment is revision bariatric surgery, most commonly laparoscopic resection of the afferent limb, which ranged in length from 3 to 22 cm in one study (mean of 7.6 cm) (3). Symptoms resolve after revision surgery in most patients. Surgeons should minimize the length of the blind afferent loop left at the time of initial RYGB to prevent candy cane Roux syndrome. Endomina (Endo Tools Therapeutics, Gosselies, Belgium) is a CE marked device that may be attached to an endoscope inside the body and allows remote actuation of the device during a peroral intervention. It offers the possibilities of making transoral full thickness tissue apposition and may allow performing, via a transoral route, large plications with tight serosa to serosa apposition.

NCT ID: NCT03577873 Completed - Complication Clinical Trials

RCT on Necessity of Cholecystectomy for Patients After Clearance of Bile Duct Stones

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

To discuss necessity of cholecystectomy for patients with stones in their bile ducts and gallbladders in the absence of absolute operation indications of cholecystectomy after clearance of bile duct stones with ERCP.

NCT ID: NCT03558243 Recruiting - Complication Clinical Trials

Prevention of Radial Artery Occlusion: Comparison of Three HEmostatiC Methods in Transradial Intervention

PROTHECT
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates three hemostatic methods for prevention of radial artery occlusion. One third of patients will receive patent hemostasis, another third will receive patent hemostasis plus ulnar compression and the last third will receive the StatSeal hemostatic disc.

NCT ID: NCT03556995 Completed - Obesity Clinical Trials

Suggesting Score Scale for Risk of Bleeding in Bariatric Surgery

Start date: January 1, 2013
Phase:
Study type: Observational

As bleeding is a major risk in bariatric surgeries, we aimed our study to find any predictors to such bleeding within the surgery or 30 days after surgery. The study is a retrospective study collecting patients data, surgeons data, and hospitals data in order to find if any of the factors influencing patients, surgeons or hospitals, has to do with bleeding in these surgeries and if it does impact bleeding in what way. The goal is finding a predictor that it's neutralizing may prevent bleeding in bariatric surgeries.

NCT ID: NCT03547232 Recruiting - Acute Pancreatitis Clinical Trials

Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)

INDOMAP
Start date: June 1, 2024
Phase: Phase 4
Study type: Interventional

Acute pancreatitis (AP) is an inflammatory condition of the pancreas following the activated pancreatic enzymes induced by varied causes, with or without other organ(s) dysfunction. The production and release of inflammatory factors is generally considered as the key factor of pathogenesis. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly applied agents for inflammatory diseases. A series studies have proved that indomethacin can reduce the risk of post-endoscopic retrograde cholangiopancreatography (ERCP), but high-quality evidence is still lacking in the field of effectiveness of NSAIDs to treat, rather than prevent, other types of AP. Majority of animal experiments showed that NSAIDs had protective effects for organ functions, but the results of several preliminary clinical studies were inconsistent. Randomized controlled trials are eagerly awaited to elucidate its effects on AP.

NCT ID: NCT03501927 Terminated - Surgery Clinical Trials

Focused Cardiac Ultrasound in Surgery

PreOPFOCUS
Start date: May 7, 2018
Phase: N/A
Study type: Interventional

Mortality and morbidity remain high after non-cardiac surgery. Known risk factors include age, high ASA grade and emergency surgery. Point-of-care focused cardiac ultrasound may elucidate pathology and potential hemodynamic compromise unknown to handling physicians. This study aims to investigate the effects of focused cardiac ultrasound in high-risk patients undergoing non-cardiac surgery with respect to clinical endpoints.

NCT ID: NCT03391687 Recruiting - Gastric Cancer Clinical Trials

Incidence of Pancreatic Fistula After Radical Gastrectomy

Start date: December 1, 2017
Phase: N/A
Study type: Observational

This study is designed to investigate the incidence of pancreatic fistula after radical gastrectomy in gastric cancer patients.

NCT ID: NCT03375268 Recruiting - Complication Clinical Trials

Predictive Model for Postoperative Complications in Hemi-hip Arthroplasty

Start date: January 1, 2011
Phase: N/A
Study type: Observational

The purpose of this study was to identify the major complications and their risk factors of elderly patients who had undergone Hemi-hip Arthroplasty.

NCT ID: NCT03324698 Active, not recruiting - Clinical trials for Chronic Pancreatitis

The Natural History of Chronic Pancreatitis

Start date: January 1, 2000
Phase: N/A
Study type: Observational

Chronic pancreatitis (CP) is a disease characterized by inflammation and their replacement by fibrotic tissue. The destruction of pancreatic function and structure are the main complications. This retrospective-prospective, multicenter, cohort study was conducted. This study aimed to observe the natural history of CP in China, analyse the risk factors for CP complications, and establish individual predictions.