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Colorectal Neoplasms clinical trials

View clinical trials related to Colorectal Neoplasms.

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NCT ID: NCT04684095 Recruiting - Cancer Clinical Trials

The Effect of ePRO on Quality of Life and Prognosis of Patients With Unresectable Metastatic Colorectal Cancer

Start date: May 26, 2021
Phase: N/A
Study type: Interventional
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NCT ID: NCT04683744 Recruiting - Clinical trials for Colorectal Cancer Screening

Facilitators and Barriers to Cancer Screening: Stakeholder Perspectives on Implementation

Start date: January 11, 2021
Phase:
Study type: Observational

The rate of screening for colorectal cancer (CRC) in the U.S. remains low (under 65%), meaning that thousands of people die of colorectal cancer unnecessarily. Colorectal cancer screening tests range from more invasive and very sensitive for polyps and cancer (colonoscopy) to less invasive and less sensitive (e.g., fecal immunochemical testing (FIT)). Screening rates go up when patients consider all these tests, not just colonoscopy. Informing patients about their options for CRC screening could produce higher quality decisions, improve the match between patient preferences and tests performed, and increase uptake of CRC screening. Decision aids (DAs) are a promising tool for accomplishing this goal. Also, precision CRC prevention - providing information about an individual's specific risk for CRC - has great promise to increase uptake and improve decision making. Unfortunately, the COVID-19 pandemic is causing severe challenges to providing CRC screening and other prevention services. Health systems are trying to adapt, but these efforts have only begun and are poorly understood. Moreover, patient perceptions of disease risk and risk from COVID-19 are unknown.

NCT ID: NCT04680260 Recruiting - Colorectal Cancer Clinical Trials

OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer

OPTIMISE
Start date: October 25, 2021
Phase: Phase 2
Study type: Interventional

A study investigating if analysis of circulating tumor DNA (ctDNA) can guide adjuvant treatment in patients with advanced colorectal cancer (CRC)

NCT ID: NCT04678011 Recruiting - Clinical trials for Familial Adenomatous Polyposis

A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

Start date: November 24, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.

NCT ID: NCT04677998 Recruiting - Clinical trials for Familial Adenomatous Polyposis

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Start date: November 24, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)

NCT ID: NCT04673955 Recruiting - Clinical trials for Metastatic Colorectal Carcinoma

BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment

BERING-CRC
Start date: September 3, 2020
Phase:
Study type: Observational
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NCT ID: NCT04668976 Recruiting - Colorectal Cancer Clinical Trials

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

Start date: November 25, 2020
Phase: Phase 2
Study type: Interventional

This study is being done to answer the following question: Is the combination of the Medtronic pump and the Codman catheter device a safe alternative to the C3000 Codman pump for delivering chemotherapy directly into the liver of patients with metastatic colorectal cancer or cholangiocarcinoma?

NCT ID: NCT04668872 Recruiting - Colorectal Cancer Clinical Trials

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Start date: December 7, 2020
Phase:
Study type: Observational

The purpose of this study is to study the way radioembolization works by collecting biopsy samples of participants' tumors after the procedure. This research may improve the way that radioembolization is performed, which could help people whose cancer has spread to the liver. The research may also provide information about how tumors respond to radioembolization.

NCT ID: NCT04666727 Recruiting - Clinical trials for Colorectal Carcinoma

Role of Diet on the Microbiome of the Digestive System

Start date: September 29, 2020
Phase:
Study type: Observational

This study is to learn more about how diet affects the microbiome (bacteria and microorganisms) of the digestive system. Researchers want to learn if this, in turn, has an effect on if and how people then develop colorectal cancer.

NCT ID: NCT04666688 Recruiting - Colorectal Cancer Clinical Trials

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Start date: December 15, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Tislelizumab in Patients with Metastatic Solid Tumors