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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors — PROSPER  

Colorectal Cancer Clinical Trial

Official title:
An Open-Label, Phase 1/2 Dose Escalation, Dose Expansion and Cohort Expansion Study Evaluating the Safety, PK and Clinical Activity of FMC-376 in Participants With KRAS G12C Mutated Locally Advanced Unresectable or Metastatic Solid Tumors

Clinical Trial Summary

The goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations. This clinical trial will be conducted in 3 parts: Phase 1A (Dose Escalation), Phase 1B (Dose Expansion), and Phase 2 (Cohort Expansion). Multiple dose levels in participants with advanced solid tumors will be evaluated.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06244771
Study type Interventional
Source Frontier Medicines Corporation
Contact Andrew Krivoshik, MD, PhD
Phone +1 (650) 457-1005
Email andrew.krivoshik@frontiermeds.com
Status Recruiting
Phase Phase 1/Phase 2
Start date February 12, 2024
Completion date April 2028
View Details
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