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NCT04815525 Clinical Trial

The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong

Colorectal Cancer Clinical Trial

— ACNC  

Official title:
The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04815525
Other study ID # 2020.597
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 1, 2023
Est. completion date December 31, 2026

Study information
Verified date February 2024
Source Chinese University of Hong Kong
Contact Felix Sia
Phone +85226370428
Email felix.sia@cuhk.edu.hk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.

Description:

This is a territory-wide retrospective observational cohort study using the Clinical Data Analysis and Reporting System (CDARS). We will identify patients from CDARS with colonoscopy performed from 1 January 2000 to 31 October 2020. Other relevant diagnoses, procedures, concomitant drugs, laboratory parameters and pathology results will be retrieved and studied.

Recruitment information / eligibility
Status Recruiting
Enrollment 5000
Est. completion date December 31, 2026
Est. primary completion date December 1, 2026
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: 1. All patients with colonoscopy performed in HA hospitals during the study period would be eligible for screening. Exclusion Criteria: 1. Patients with documented personal history of colorectal cancers before the study period would be excluded.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Hong Kong Prince of Wales Hospital Shatin New Territories

Sponsors (1)
Lead Sponsor Collaborator
Chinese University of Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome
Type Measure Description Time frame Safety issue
Primary Culumative incidence of advanced colorectal neoplasia high-risk adenomas or CRC after 15 years of index conoloscopy 15 years
Secondary CRC-related mortality rate the rate of mortality due to CRC-related incidents 15 years
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