Ultrasound-Guided Erector Spinae Plan Block for Colorectal Surgery

Colorectal Cancer Clinical Trial

Official title:

The Comparison of the Erector Spinae Plane Block and Wound Infiltration on Postoperative Opioid Consumption in Patients Undergoing Laparoscopic Colorectal Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04313764
• Other study ID #: ESP Colorectal Surgery
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 18, 2020
• Est. completion date: August 15, 2020

Study information

• Verified date: June 2020
• Source: Ataturk University
• Contact: Irem Ates, MD
• Phone: 00905327401258
• Email: driremates[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Colorectal cancer is a common and lethal disease. It still remains the third most common cause of cancer death in women and the second leading cause of death in men. Pain control is an important direction of postoperative management in malignancy surgery. Inadequate pain control increases cardiac and respiratory complications in these critical patients. Erector spinae plane (ESP) block is a recently described regional anesthesia technique that blocks the dorsal and ventral rami of the spinal nerves and the sympathetic nerve fibers. While the ESP block has been shown to provide effective postoperative analgesia after thoracic, and abdominal surgeries.

Our aim in this study was to investigate bilateral thoracic ESP block for providing successful postoperative pain management following colorectal surgery.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 48
• Est. completion date: August 15, 2020
• Est. primary completion date: July 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiologist's physiologic state I-II-III patients undergoing Colorectal surgery

Exclusion Criteria:

• renal or hepatic insufficiency, chronic pain, patients with an allergic reaction to anesthesia and analgesia drugs to be used

Related Conditions & MeSH terms

• Colorectal Cancer
• Pain, Postoperative
• Postoperative Pain

Intervention

Drug:
• Bupivacaine Hcl 0.25% ESP block
Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine, per side
• Bupivacaine Hcl 0.25% infiltration
Wound infiltration with 20 ml %0.25 bupivacaine

Locations

Country	Name	City	State
Turkey	Ataturk University	Erzurum

Sponsors (1)

Lead Sponsor	Collaborator
Ataturk University

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

Hain E, Maggiori L, Prost À la Denise J, Panis Y. Transversus abdominis plane (TAP) block in laparoscopic colorectal surgery improves postoperative pain management: a meta-analysis. Colorectal Dis. 2018 Apr;20(4):279-287. doi: 10.1111/codi.14037. — View Citation

Tulgar S, Ahiskalioglu A, De Cassai A, Gurkan Y. Efficacy of bilateral erector spinae plane block in the management of pain: current insights. J Pain Res. 2019 Aug 27;12:2597-2613. doi: 10.2147/JPR.S182128. eCollection 2019. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Opioid Consumption	Opioid consumption postroperative period	Postoperative first 24 hours
Secondary	Visual Analog Pain Score	Pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain)	Postoperative first 24 hours