Colorectal Cancer, Peritoneal Carcinomatosis, Anastomosis Insufficiency Clinical Trial
Official title:
The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.
| Verified date | May 2024 |
| Source | Uppsala University Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
The role of gut microbiota in anastomosis insufficiency in patients operated for colorectal cancer and for peritoneal carcinomatosis is going to be investigated. This is a pilot study.
| Status | Completed |
| Enrollment | 45 |
| Est. completion date | January 31, 2024 |
| Est. primary completion date | January 31, 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria Colorectal group - adenocarcinom in colon or rektum - curative operation planed - direct anastomose plan - elective surgery Inclusion Criteria HIPEC group : - All patients with appendix, colon or rectal cancer accepted for CRS+HIPEC Exclusion Criteria: - Ongoing antibiotics treatment - antibiotics treatment in the last 6 months - acute surgery - palliative surgery - Ulcerös colitis or Crohns disease - Prior colectomy - Small intestine stoma before the operation - neoadjuvant treatment - Colon preparation |
| Country | Name | City | State |
|---|---|---|---|
| Sweden | Uppsala University Hospital | Uppsala |
| Lead Sponsor | Collaborator |
|---|---|
| Uppsala University Hospital |
Sweden,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Microbiome | Change in microbiome in case of insufficiency of the anastomosis | 30 days |