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Colonic Polyps clinical trials

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NCT ID: NCT05930041 Recruiting - Colonic Polyp Clinical Trials

Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Cold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized <9 mm. CSP was designed to improve the complete resection rate and reduce adverse events. Investigators hypothesize that CSP is better than conventional hot snare endoscopic mucosal resection (HS-EMR) in the presence of injured submucosal arteries detected in the submucosal layer for 10-19 mm nonpedunculated colorectal polyps, resulting in lower delayed bleeding after CSP of 10-19 mm nonpedunculated colorectal polyps.

NCT ID: NCT05870332 Recruiting - Colo-rectal Cancer Clinical Trials

Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy

NAIAD
Start date: October 16, 2023
Phase:
Study type: Observational

The goal of this trial is to determine whether use of a Computer Assisted Detection (CADe) programme leads to an increase in ADR for either units or individual colonoscopists, independent of setting or expertise

NCT ID: NCT05869838 Recruiting - Colonic Polyp Clinical Trials

A Clinical Study on Endoscopic and Histopathological Outcomes of Screening and Surveillance Colonoscopies

CODACO
Start date: March 12, 2024
Phase:
Study type: Observational

The objective of this study is to collect colonoscopy data for use in the development and testing of artificial intelligence (AI) devices for colonoscopies.

NCT ID: NCT05822895 Recruiting - Colonic Polyp Clinical Trials

Review of the Impact of a Computer-aided Real-time Polyp Detection System on Adult Colonoscopy

COPILOT
Start date: January 2, 2023
Phase:
Study type: Observational [Patient Registry]

Background: Removal of adenomatous polyps during colonoscopy is associated with long-term prevention of colorectal cancer-related deaths. Recently, there have been much interest in the use of artificial intelligence (AI) platforms to augment the routine endoscopic assessment of the colon to enhance adenoma detection rate (ADR). To date, computer assisted detection of polyps (CADe) have been shown to be safe, with a significant increase in ADR, without any concomitant increase in post-procedural complications. Aims: The investigators aim to evaluate the use of GI GeniusTM Intelligent Endoscopy Module in a multi-ethnic Asian population (Singapore) to increase in ADR and adenoma detected per colonoscopy (ADPC)to justify its effectiveness as an adjunct in polyp detection and training for colonoscopy. Methods: This study will be a single-institution cohort study, conducted over a 2-year period. Sengkang General Hospital (SKH) does an estimated 12,500 colonoscopies per year, with an average of 1,040 colonoscopies performed every month. Thus, given the case volume, the investigators expect to detect differences in ADR amongst endoscopists if any during this study period. As part of the subgroup analysis, the investigators also aim to compare the ADR rates of trainee endoscopists with and without the GI GeniusTM Intelligent Endoscopy Module to ascertain its utility as an education tool/training adjunct

NCT ID: NCT05737017 Recruiting - Colonic Polyps Clinical Trials

The Efficacy and Safety of a Hybrid Hemostatic Device (ClearCoajet)

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The ClearCoajet is a new hemostasis device with a hybrid function (Coagulation + Injection) and is developed to provide effective coagulation, injection, and marking around lesions without changing devices during the endoscopic procedure. In this study, the investigators examine the hemostatic effect of ClearCoajet on intraprocedural bleeding during endoscopic mucosal resection or endoscopic submucosal dissection for colorectal sessile polyps or lateral growth tumors larger than 1.5 cm. The investigators also aim to compare the delayed bleeding and recurrence rates between the ClearCoajet group and the control group.

NCT ID: NCT05730192 Recruiting - Colorectal Cancer Clinical Trials

EAGLE Trial CADDIE Artificial Intelligence Endoscopy

EAGLE
Start date: May 10, 2023
Phase: N/A
Study type: Interventional

The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.

NCT ID: NCT05611151 Recruiting - Colorectal Cancer Clinical Trials

Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy

COLOWISE
Start date: April 30, 2023
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, randomized study to evaluate the clinical performance of a novel CADe device, WISE VISION® Endoscopy System, in patients undergoing high-definition white light (HDWL) colonoscopy for screening or surveillance of colorectal Cancer (CRC). Eligible subjects who meet the study inclusion/exclusion criteria will be randomized in a 1:1 ratio to undergo colonoscopy : - Experimental: CADe colonoscopy procedure with WISE VISION® Endoscopy (CADe Group) - Control: Standard Colonoscopy without CADe (Standard Colonoscopy Group)

NCT ID: NCT05517343 Recruiting - Depression Clinical Trials

Impact of Real-time Notification of Colonoscopic Optical Diagnosis on Patients' Anxiety and Depression After Polypectomy

Start date: August 20, 2022
Phase: N/A
Study type: Interventional

The accuracy of endoscopic optical diagnosis for colorectal polyps has been approaching histological diagnosis after implementation of image enhancement endoscopic technologies. The real-time notification of possible nature of resected polyp after colonoscopy is expected to reduce the anxiety and depression level of the patients before the availability of histological diagnosis and improve their quality of life. We designed and conducted a randomized control trial to confirm this hypothesis.

NCT ID: NCT05466903 Recruiting - Colonic Polyp Clinical Trials

Prospective, Randomized, Parallel Clinical Controlled Study of Early Diet Opening on Postoperative Gastrointestinal Hemorrhage in Patients With Colonic Polyps

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Currently, hemorrhage remains the most common postoperative complication in patients with colon polyps, with an incidence of approximately 1.5%. The main reasons for postoperative hemorrhage are: the patient's own condition, the nature of the polyp and the operation. The number of patients treated for colon polyps has increased, postoperative care is confusing, medical resources are wasted, and the time span for postoperative diet recovery is large. However, studies on the effect of postoperative dietary recovery timing on postoperative polyp bleeding are rare.

NCT ID: NCT05322993 Recruiting - Colonic Polyp Clinical Trials

Improving Polyp Detection Rate by Artificial Intelligence in Colonoscopy

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to investigate if the use of artificial intelligence (AI) in colonoscopy improves the polyp detection rate, and if the use of AI has a learning effect.