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Underwater EMR vs. Conventional EMR for Large Non-pedunculated Colonic Polyp

Colonic Polyp Clinical Trial

Official title:
Efficacy and Safety of Underwater Endoscopic Mucosal Resection Versus Conventional Endoscopic Mucosal Resection for the Treatment of Large Non-pedunculated Colonic Lesions. Multicentric Randomized Controlled Trial

Clinical Trial Summary

To analyse the efficacy and safety of two standard methods of endoscopic mucosal resection (EMR) for large non-pedunculated colorectal polyps, the investigators will compare submucosal injection-assisted endoscopic mucosal resection (SEMR) versus underwater endoscopic mucosal resection, without submucosal injection (UEMR).

Clinical Trial Description

Underwater endoscopic mucosal resection (UEMR) emerges as a variant of traditional resection, in which a submucosal cushion formation is not necessary. This technique was described in 2012 by Kenneth Binmoeller based on the physical floating effect of colonic mucous membrane by filling the colonic lumen using water instead of air. This "floating effect" conditions the natural separation of the colonic wall layers, allowing the distension of the submucosal space without the need to inject substances into it. On the other hand, performing resection in liquid medium conditions could drive the benefit of heat dissipation caused by the current, which would reduces thermal damage caused to the tissues. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03567746
Study type Interventional
Source Parc de Salut Mar
Contact Joaquin Rodriguez, MD PhD
Phone 926278000
Email joakinrodriguez@gmail.com
Status Recruiting
Phase N/A
Start date June 4, 2018
Completion date December 30, 2019
View Details
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