Linked-color Imaging for the Detection of Colorectal Flat Lesions

Status Completed

Clinical Trial Summary

Linked color imaging (LCI) was recently developed and uses a laser endoscopic system (Fujifilm Co, Tokyo, Japan) that acquires images by simultaneously using narrow-band short-wavelength light and white-light (WL) in an appropriate balance. LCI is a new image-enhancing technology that is intended to enhance slight color differences in the red region of the mucosa. The acquired color information is reallocated to differentiate colors that are similar to the mucosal color, resulting in improved performance in depicting blood vessels, and additional image processing that enhances color separation for red color permits clear visualization of red blood vessels and white pits. This modality may increase the detection rate of colorectal polyps by enhancing the visibility of colonic mucosal vessels. In addition, it has been reported that LCI increases the visibility of colorectal flat lesions and contributes to improvement of the detection rate for these lesions. The primary aim of the current study was to compare the detection rate of colorectal flat lesions of LCI cap-assisted colonoscopy with WL cap-assisted colonoscopy in prospective randomized trial. In addition, we prospectively compared LCI and WL with regard to the visibility of colorectal flat lesions found in this study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03272945
Study type	Interventional
Source	Showa Inan General Hospital
Contact
Status	Completed
Phase	N/A
Start date	September 6, 2017
Completion date	December 31, 2018

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06062095` - Computer Aided Diagnosis (CADx) for Colorectal Polyps Resect-and-Discard Strategy	N/A
Not yet recruiting	`NCT02688699` - Additive Hemostatic Efficacy of EndoClot After EMR or ESD in the Gastrointestinal Tract	Phase 4
Active, not recruiting	`NCT03962868` - Endoscopic Submucosal Dissection (ESD) Versus Endoscopic Mucosal Resection (EMR) for Large Non Pedunculated Colonic Adenomas: a Randomized Comparative Trial	N/A
Not yet recruiting	`NCT05776381` - The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp	Phase 2
Recruiting	`NCT04157803` - Accuracy of aCETIC Acid to Predict Histopathology of Colonic Polyps	N/A
Completed	`NCT03758872` - CUFF-assisted Colonoscopy vs Standard Colonoscopy
Recruiting	`NCT05870332` - Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy
Completed	`NCT03690297` - Linked Color Imaging (LCI) for Colorectal Adenoma Detection	N/A
Recruiting	`NCT03865537` - Cold Snare Endoscopic Mucosal Resection Trial	N/A
Recruiting	`NCT04149184` - Computer-aided Detection Device in Standard Colonoscopy	N/A
Recruiting	`NCT05099432` - The CARMA Technique Study	N/A
Withdrawn	`NCT04778566` - Evaluating the Cologuard Test for Use in Lynch Syndrome
Withdrawn	`NCT01372696` - Endoscopic Characteristics of Colonic Tumours	N/A
Recruiting	`NCT05322993` - Improving Polyp Detection Rate by Artificial Intelligence in Colonoscopy	N/A
Completed	`NCT03121495` - Study on Second Forward View Examination in the Right Colon	N/A
Completed	`NCT03344055` - Endocuff-assisted Colonoscopy vs Standard Colonoscopy on Adenoma Detection Rate	N/A
Recruiting	`NCT06063720` - Effective Withdrawal Time and Adenoma Detection Rate
Recruiting	`NCT04220905` - Endoscopic Resection of Large Colorectal Polyps: An Observational Cohort Study
Completed	`NCT04693078` - Detection of Colonic Polyps Via a Large Scale Artificial Intelligence (AI) System	N/A
Completed	`NCT05242562` - Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life	N/A