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Cognitive Training clinical trials

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NCT ID: NCT05198726 Recruiting - Clinical trials for Mild Cognitive Impairment

Speed of Processing (SoP) Training Plus α-tACS

aMCIUp
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

The current proposal aims to assess if the combination of Speed of Processing (SoP) training with alpha tACS (α-tACS) is able to increase brain speed of processing as assessed by the Useful Field of View (UFOV) when comparing to SoP training plus sham α-tACS. Moreover, a second aim is to assess if those changes in speed of processing transfer to other cognitive domains, such as memory, language and executive functioning. Furthermore, the mechanisms underlying these interventions will be tested, namely to assess brain connectivity and coherence as assessed by EEG. To that purpose, the aim of the current proposal is to conduct a double-blind, parallel randomized trial assessing the effects of combining SoP with alpha endogenous tACS (either active or sham) in participants with Mild Cognitive impairment (MCI).

NCT ID: NCT04615169 Completed - Aging Clinical Trials

Multi-component Cognitive Intervention for Older Adults With Mixed Cognitive Abilities

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Objective: To assess the feasibility and preliminary effectiveness of an evidence-driven, pragmatic multi-component cognitive intervention with simulated everyday tasks (MCI-SET) with an inclusive group design in community centers Methods: One group, pre-test, post-test, and 3-month follow up research design. The participants who were >=65 and frail, dependence in >= one activity of daily living, or with a confirmed dementia from eight community centers. MCI-SET consisted 12 two-hour weekly group sessions. Feasibility was described with intervention development, fidelity, and acceptability. Outcomes included general daily functioning, general cognition, memory, attention, executive functioning, and processing speed.

NCT ID: NCT03950648 Withdrawn - Cognitive Training Clinical Trials

Spatial Cognitive Training for Chronic Vestibular Disorders

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

In this study the investigators propose to apply cognitive training, which has been largely used in the realm of age-related cognitive decline, dementia, and Alzheimer's disease, in a novel clinical context to individuals with vestibular impairment. In prior work the investigators observed that individuals with vestibular loss have evidence of spatial cognitive impairment. The investigators plan to evaluate the preliminary efficacy and feasibility of a cognitive training program in a sample of participants with chronic vestibular impairment who display deficits in spatial ability. The cognitive training program will focus on visuospatial skills and will be used as an adjunct to traditional vestibular physical therapy (VPT).

NCT ID: NCT03790696 Completed - Anxiety Disorders Clinical Trials

Novel Anxiety Treatment

Start date: February 2, 2017
Phase: N/A
Study type: Interventional

The first aim of this study, as mentioned in the attached NIH grant, is to test the feasibility and acceptability of a novel computer-based cognitive training program that is designed to rehabilitate the brain's ventral attention network (VAN), a brain system associated with anxiety disorders. Once feasibility and acceptability is determined the investigators will begin aim 2 where the investigators will test the efficacy of this novel treatment, which could reduce the symptoms of anxiety disorders in children (and adults) by training them to actively ignore stimuli in turn reducing the activity of the VAN. To test this potential treatment the investigators will recruit 60 children with anxiety disorders and 10 healthy children to compare an active version of a computer training program to a sham version of training. The investigators will also measure VAN reactivity before and after treatment using functional magnetic resonance imaging (fMRI). The rationale of this research is that it could lead to a novel, safe, mechanism-based treatment for a major public health problem.

NCT ID: NCT03419052 Completed - Cognition Clinical Trials

MINDSpeed Food and Brain Training RCT

MINDSpeed
Start date: January 10, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to learn how foods high in polyphenols and brain training exercises affect older adults' cognitive performance

NCT ID: NCT01616797 Completed - Depression, Anxiety Clinical Trials

A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan

Start date: February 2014
Phase: N/A
Study type: Interventional

The research proposes to use an innovative solution to shape brain circuits that support executive function and emotion reactivity -using targeted neurobehavioral intervention.