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Clubfoot clinical trials

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NCT ID: NCT01238484 Terminated - Diabetes Mellitus Clinical Trials

Ankle Equinus Contracture Treated With Dynamic Splinting

Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the Ankle Dorsiflexion Dynasplint System (DS) is effective in treating contracture for patients with Ankle Equinus secondary to diabetes mellitus.

NCT ID: NCT01088828 Completed - Clubfoot Clinical Trials

Exploring the Causes of Clubfoot Using Magnetic Resonance Imaging, MRI

Start date: May 2010
Phase: N/A
Study type: Observational

The purpose of this study is to: 1. compare structural variations observed in the calf and foot of the clubfoot mouse model(pma)with human clubfoot patients antenatally and postnatally; 2. identify features that might be used in future large scale studies to delineate a subtype of human clubfoot associated with lack of response to standard 'Ponseti' manipulation treatments.

NCT ID: NCT01067651 Completed - Clubfoot Clinical Trials

Comparison of Casting Materials for the Treatment of Clubfoot Using the Ponseti Method

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study was to determine the influence of cast material on correction of congenital idiopathic clubfeet using the Ponseti method.

NCT ID: NCT01050088 Not yet recruiting - Clubfoot Clinical Trials

Sucrose Analgesia in Infants Undergoing Casting for Club Foot

SCF
Start date: March 2010
Phase: N/A
Study type: Interventional

Babies with congenital clubfeet are treated by the Ponseti casting method. The procedure may cause discomfort to the patient. This study will examine the use of 5 CC Sucrose solution as a comforting agent for the babies.

NCT ID: NCT00825097 Completed - Stroke Clinical Trials

Efficacy Study of Selective Tibial Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic Patients

Neurotomy
Start date: October 2008
Phase: Phase 3
Study type: Interventional

Spastic equinovarus foot (SEF) is a major cause of disability in stroke patients. Treatments may include physical therapy, orthosis, botulinum toxin (BTX) injections and selective neurotomy. Several RCT placebo-controlled studies have demonstrated improvement in spasticity, in pain and in active ankle dorsiflexion after BTX injections. Unfortunately, BTX is an expensive treatment and its effects last about three months. Selective neurotomy consists in a partial section of the motor nerve innervating spastic muscles responsible for the SEF, leading to a permanent treatment of the SEF. Until now, neurotomy has only been assessed by observational case-report studies and has never been submitted to a RCT. The aim of our study is to evaluate the benefits of selective tibial neurotomy in case of SEF according to the 3 domains of the ICF, by comparing it with BTX injections, among a prospective, randomized, controlled single blind study: it would allow to promote a permanent and cost-effective treatment in case of SEF.

NCT ID: NCT00607191 Completed - Clubfoot Clinical Trials

Clubfoot DNA Repository

Start date: January 2008
Phase: N/A
Study type: Observational

To build a DNA repository to enable participation in ongoing and future Clubfoot genetic linkage studies.

NCT ID: NCT00475631 Withdrawn - Clubfoot Clinical Trials

Economic Evaluation of Clubfoot Treatment: One Centre's Experience

Start date: October 2003
Phase:
Study type: Observational

Purpose: The purpose of the study is to complete a cost analysis of the different methods used for clubfoot treatment. Objectives: Short-term objective: To explore the experience of British Columbia Children's Hospital (BCCH) with costs and outcomes related to the various forms of clubfoot management since 1984 to present. Long-term objective: To use the information gathered in this project and apply it to future studies in the clubfoot research program and to do a complete cost-benefit analysis. Hypothesis: The hypothesis of the study is that the BCCH clubfoot treatment program has better outcomes in terms of reduced financial costs than the traditional surgical management.

NCT ID: NCT00474344 Completed - Clubfoot Clinical Trials

Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)

Start date: August 2004
Phase:
Study type: Observational

The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations. Towards this goal, in preliminary studies, Dr. Hecht's group has identified two genes, NAT2 and CASP10, which demonstrate evidence for linkage and association to ITEV.

NCT ID: NCT00474032 Recruiting - Clubfoot Clinical Trials

Using Botox to Treat Patients With Idiopathic Clubfoot

Start date: March 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of treatment of idiopathic clubfoot utilizing Botulinum Toxin Type A (Botox). This is not a hypothesis-generating study as we are reporting on outcomes of patients who have been treated by this method of clubfoot treatment.

NCT ID: NCT00210431 Completed - Cerebral Palsy Clinical Trials

Post Marketing Surveillance Study of Dysport

Start date: October 2004
Phase:
Study type: Observational

The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.